HIV and Cardiovascular Disease: Update on Clinical Events, Special Populations, and Novel Biomarkers.
HIV and Cardiovascular Disease: Update on Clinical Events, Special Populations, and Novel Biomarkers.
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DOI：
10.1007/s11904-018-0400-5
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发表时间：
2018-06
影响因子：
4.6
通讯作者：
Freiberg MS
中科院分区：
文献类型：
--
作者：
So-Armah K;Freiberg MS
本综述的目的是提供一个更新的HIV感染和心血管疾病之间的联系。我们将集中我们的审查主要是文献描述的临床心血管事件和未充分研究的重要主题。在高活性抗逆转录病毒治疗时代，心力衰竭、外周动脉疾病和卒中是HIV感染背景下值得更多关注的CVD模式。低收入和中等收入国家艾滋病毒感染人群的临床心血管疾病发病率数据有限。多物质使用在HIV中很常见，但作为HIV和CVD之间关联的调节剂或介导剂的研究不足。HIV的CVD风险评估仍然具有挑战性，但对新型生物标志物的新研究可能会提供进一步的见解。在我们试图理解、量化和预测PLWHA中心血管疾病风险时，也需要纳入非生物因素。产生和检验假说以了解HIV心肌梗死的机制已受到极大关注。在资源有限的环境中和HIV药物使用者中，心力衰竭、PAD、中风和心血管疾病风险也值得关注。
The objective of this review is to provide an update on the link between HIVinfection and cardiovascular disease (CVD). We will focus our review mainly on literature describing clinical CVD events and understudied topics of importance. Heart failure, peripheral artery disease, and stroke are CVD modalities deserving more attention in the context of HIV infection in the highly active antiretroviral therapy era. Incidence data on clinical CVD from HIV populations in low- and middle-income countries are limited. Multisubstance use is common in HIV, but understudied as a moderator or mediator of the association between HIV and CVD. CVD risk assessment in HIV remains challenging, but new research into novel biomarkers may provide further insights. There is also a need for inclusion of non-biologic factors in our attempts to understand, quantify, and predict CVD risk among PLWHA. Significant attention has been paid to generating and testing hypotheses to understand the mechanisms of myocardial infarction in HIV. Similar attention is deserving for heart failure, PAD, stroke, and cardiovascular disease risk in resource-limited settings and among substance users with HIV.
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成年马拉维人在艾滋病毒护理中的高血压，糖尿病和心血管危险因素的负担：综合服务的后果。
影响因子：
4.5
作者：
Divala OH;Amberbir A;Ismail Z;Beyene T;Garone D;Pfaff C;Singano V;Akello H;Joshua M;Nyirenda MJ;Matengeni A;Berman J;Mallewa J;Chinomba GS;Kayange N;Allain TJ;Chan AK;Sodhi SK;van Oosterhout JJ
通讯作者：
van Oosterhout JJ
DOI：
10.1097/qai.0000000000001450
发表时间：
2017-08-15
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Drozd DR;Kitahata MM;Althoff KN;Zhang J;Gange SJ;Napravnik S;Burkholder GA;Mathews WC;Silverberg MJ;Sterling TR;Heckbert SR;Budoff MJ;Van Rompaey S;Delaney JAC;Wong C;Tong W;Palella FJ;Elion RA;Martin JN;Brooks JT;Jacobson LP;Eron JJ;Justice AC;Freiberg MS;Klein DB;Post WS;Saag MS;Moore RD;Crane HM
通讯作者：
Crane HM
影响因子：
4.6
作者：
Bertrand L;Dygert L;Toborek M
通讯作者：
Toborek M
影响因子：
11.8
作者：
Althoff, Keri N.;McGinnis, Kathleen A.;Justice, Amy C.
通讯作者：
Justice, Amy C.
影响因子：
3.7
作者：
Dimala, Christian Akem;Atashili, Julius;Monekosso, Gottlieb L.
通讯作者：
Monekosso, Gottlieb L.