Consumption of dried-bonito broth acutely increases peripheral blood flow in humans
Consumption of dried-bonito broth acutely increases peripheral blood flow in humans
复制标题
食用干鲣鱼汤会急剧增加人体末梢血流量
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
T. Noguchi
中科院分区：
文献类型：
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作者：
Yoshizu Nozawa;M. Kuroda;T. Noguchi
我们用激光多普勒血流仪研究了单剂鱼干肉汤(DBB)对外周血流量的急性影响。在一项随机、双盲、交叉、安慰剂对照研究中，19名健康女性受试者服用DBB(4900毫克)或安慰剂。在进食前和进食后5、10、15、20、25、30、45和60min测量外周血流量。摄入DBB后血流量显著增加，服用DBB 60min(AUC0-60)的血流量-时间曲线下的血流量显著高于服用安慰剂(p<；0.001)。服用小剂量DBB(2450 Mg)后，观察到外周血流量增加，服用DBB后AUC0-60显著高于服用安慰剂后(p<；0.01)。4900 mg DBB组的平均AUC0-60约为2450 mg DBB组的2倍，提示单剂量口服DBB对外周血流量可能有急性剂量依赖效应。
We investigated the acute effect of a single dose of dried-bonito broth (DBB) on peripheral blood flow using a laser Doppler blood flow meter. In a randomized, double-blind, crossover, placebo-controlled study, 19 healthy female subjects ingested DBB (4900mg) or placebo. The peripheral blood flow was measured before ingestion and at 5, 10, 15, 20, 25, 30, 45, and 60min after ingestion of the test diet. Blood flow significantly increased after DBB ingestion, and th ea rea under the blood flow-time curves calculated up to 60min (AUC0‐60 )f or the ingestion with DBB was significantly higher than that for the placebo ingestion (p < 0.001). Following consumption of lower dose of DBB (2450mg), an increase in peripheral blood flow was observed and that the AUC0‐60 after subjects consumed DBB was significantly higher than that after they consumed the placebo (p < 0.01). The mean AUC0‐60 fo rt he treatment with 4900mg DBB was about 2 times that for 2450mg DBB, suggesting that an orally administered single dose of DBB might have an acute dose-dependent effect on peripheral blood flow.
DOI：
10.1073/pnas.85.9.3175
发表时间：
1988-05-01
影响因子：
11.1
作者：
KOHEN, R;YAMAMOTO, Y;AMES, BN
通讯作者：
AMES, BN