Power training alters somatosensory cortical activity of youth with cerebral palsy.
Power training alters somatosensory cortical activity of youth with cerebral palsy.
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DOI：
10.1002/acn3.51545
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发表时间：
2022-05
影响因子：
5.3
通讯作者：
Kurz, Max J.
中科院分区：
文献类型：
--
作者：
Bergwell, Hannah;Trevarrow, Mike;Corr, Brad;Baker, Sarah;Reelfs, Heidi;Wilson, Tony W.;Moreau, Noelle G.;Kurz, Max J.
我们以前的脑磁图（MEG）研究表明，脑瘫（CP）的人有较弱的体感皮层活动比神经型（NT）的控制，这是与减少肌肉力量和流动性。力量训练可以提高脑瘫青年的下肢等速肌力、肌肉力量和步行能力。潜在地，这些临床相关的改善部分是由躯体感觉处理的变化驱动的。本研究的目的是确定力量训练是否对CP青年的肌肉功能和体感皮层活动有补充性的改变。一组青年CP患者（N = 11;年龄= 15.90 ± 1.1岁）和NT对照组（N = 10;年龄= 15.93 ± 2.48岁）参与了本研究。患有CP的青少年接受了24次力量训练。使用术前-术后双侧腿部推举1次重复最大值（1 RM）、峰值功率产生、10 m步行速度和1 min步行距离作为结局指标。MEG神经成像评估了休息时体感皮层活动的变化。NT对照仅进行基线MEG评估。患有CP的青少年的1 RM增加了56%（p < 0.001），峰值功率增加了33%（p = 0.019），1分钟步行改善了4%（p = 0.029）。值得注意的是，体感皮层活动增加了46%（p = 0.02）。这些结果首次表明，力量训练与CP患者的肌肉功能、步行能力和静息体感皮层活动的改善有关。这种治疗方法可能是有利的，因为它有可能促进皮质和肌肉的可塑性，这似乎对改善行走性能有延续作用。
Our prior magnetoencephalographic (MEG) investigations demonstrate that persons with cerebral palsy (CP) have weaker somatosensory cortical activity than neurotypical (NT) controls, which is associated with reduced muscular strength and mobility. Power training can improve lower extremity isokinetic strength, muscular power, and walking performance of youth with CP. Potentially, these clinically relevant improvements are partially driven by changes in somatosensory processing. The objective of this investigation was to determine if power training has complementary changes in muscular function and somatosensory cortical activity in youth with CP. A cohort of youth with CP (N = 11; age = 15.90 ± 1.1 years) and NT controls (N = 10; Age = 15.93 ± 2.48 years) participated in this investigation. Youth with CP underwent 24 power training sessions. Pre‐post bilateral leg press 1‐repetition maximum (1RM), peak power production, 10‐m walking speed, and distance walked 1‐min were used as outcome measures. MEG neuroimaging assessed the changes in somatosensory cortical activity while at rest. NT controls only underwent a baseline MEG assessment. Youth with CP had a 56% increase in 1RM (p < 0.001), a 33% increase in peak power production (p = 0.019), and a 4% improvement in 1‐min walk (p = 0.029). Notably, there was a 46% increase in somatosensory cortical activity (p = 0.02). These results are the first to show that power training is associated with improvements in muscular function, walking performance, and the resting somatosensory cortical activity in individuals with CP. This treatment approach might be advantageous due to the potential to promote cortical and muscular plasticity, which appear to have carryover effects for improved walking performance.
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DOI：
10.1111/j.1469-8749.2003.tb00954.x
发表时间：
2003-08-01
影响因子：
3.8
作者：
Elder, GCB;Kirk, J;Leahey, L
通讯作者：
Leahey, L
影响因子：
2.4
作者：
Akkaya, Kamile Uzun;Elbasan, Bulent
通讯作者：
Elbasan, Bulent
影响因子：
56.9
作者：
DUFFY, FH;BURCHFIE.JL
通讯作者：
BURCHFIE.JL
影响因子：
3.8
作者：
Gordon, AM
通讯作者：
Gordon, AM
影响因子：
5.7
作者：
Grefkes, C;Geyer, S;Zilles, K
通讯作者：
Zilles, K