Software for computing and annotating genomic ranges.
Software for computing and annotating genomic ranges.
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DOI:
10.1371/journal.pcbi.1003118
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发表时间:
2013
影响因子:
4.3
通讯作者:
Carey VJ
中科院分区:
文献类型:
--
作者:
Lawrence M;Huber W;Pagès H;Aboyoun P;Carlson M;Gentleman R;Morgan MT;Carey VJ
We describe Bioconductor infrastructure for representing and computing on annotated genomic ranges and integrating genomic data with the statistical computing features of R and its extensions. At the core of the infrastructure are three packages: IRanges, GenomicRanges, and GenomicFeatures. These packages provide scalable data structures for representing annotated ranges on the genome, with special support for transcript structures, read alignments and coverage vectors. Computational facilities include efficient algorithms for overlap and nearest neighbor detection, coverage calculation and other range operations. This infrastructure directly supports more than 80 other Bioconductor packages, including those for sequence analysis, differential expression analysis and visualization.
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影响因子:
46.9
作者:
Ji, Hongkai;Jiang, Hui;Ma, Wenxiu;Johnson, David S.;Myers, Richard M.;Wong, Wing H.
通讯作者:
Wong, Wing H.
DOI:
10.1093/bioinformatics/btq033
发表时间:
2010-03-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Quinlan AR;Hall IM
通讯作者:
Hall IM
影响因子:
12.3
作者:
Gentleman RC;Carey VJ;Bates DM;Bolstad B;Dettling M;Dudoit S;Ellis B;Gautier L;Ge Y;Gentry J;Hornik K;Hothorn T;Huber W;Iacus S;Irizarry R;Leisch F;Li C;Maechler M;Rossini AJ;Sawitzki G;Smith C;Smyth G;Tierney L;Yang JY;Zhang J
通讯作者:
Zhang J
影响因子:
5.8
作者:
Morgan, Martin;Anders, Simon;Gentleman, Robert
通讯作者:
Gentleman, Robert
影响因子:
7
作者:
Li, Heng;Ruan, Jue;Durbin, Richard
通讯作者:
Durbin, Richard