Structural correlates of commission errors in prospective memory
Structural correlates of commission errors in prospective memory
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前瞻记忆中犯错的结构相关性
DOI：
10.1016/j.cortex.2019.10.013
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发表时间：
2020
期刊：
影响因子：
3.6
通讯作者：
Bugg, Julie M.
中科院分区：
文献类型：
--
作者：
Scullin, Michael K.;Ball, B. Hunter;Bugg, Julie M.
前瞻性记忆是指记住执行预期的未来行动，例如记住在早餐时服用药物。从历史上看，该领域一直专注于最初记住前瞻性记忆任务的失败（遗漏错误），但有趣的是，个体偶尔会在完成前瞻性记忆任务后重复该任务（例如，双剂量）。这些前瞻性记忆失活/遗忘的失败被称为委托错误。目前注册的研究调查了47名健康老年人的委托错误实验室测量的结构神经影像学相关性。现存的理论在他们的预测结果不同：委员会错误的风险被预测为最高的个人与较小的内侧颞叶体积（输出监测理论），较大的外侧前额叶皮层体积（剩余激活理论），或较大的内侧颞叶体积和较小的外侧前额叶皮层体积的组合（双重机制理论）。在注册的分析中，我们发现更多的委托错误与更大的内侧颞叶/海马灰质体积相关（支持双重机制理论），但与外侧顶叶、额极或腹外侧/背外侧前额叶皮层的灰质或白色体积无关（不支持双重机制理论）。在事后分析中，较小的体积在外侧眶额皮质与更多的委员会错误，可能表明PFC控制的双重机制理论在概念上是正确的，但不同的PFC子区域比预期施加控制委员会错误。总的来说，登记和事后分析结果显示，MTL/PFC区域的功能分离与双重机制理论比其他理论更一致。
Prospective memory refers to remembering to perform an intended future action, such as remembering to take medication with breakfast. Historically, the field has focused on failures to initially remember a prospective memory task (omission errors), but interestingly, individuals will occasionally repeat a prospective memory action after it has been completed (e.g., double dosing). These failures in prospective memory deactivation/forgetting are termed commission errors. The current registered study investigated structural neuroimaging correlates of a laboratory measure of commission errors in 47 healthy older adults. Extant theories differed in their predicted outcomes: commission error risk was predicted to be highest in individuals with smaller medial temporal lobe volume (output monitoring theory), larger lateral prefrontal cortex volume (residual activation theory), or a combination of larger medial temporal lobe volume and smaller lateral prefrontal cortex volume (dual mechanisms theory). In registered analyses, we found that a higher number of commission errors was associated with larger medial temporal lobe/hippocampal grey matter volume (supporting dual mechanisms theory), but not with grey or white matter volume in the lateral parietal lobe, frontal pole, or a composite of ventrolateral/dorsolateral prefrontal cortex (not supporting dual mechanisms theory). In post hoc analyses, smaller volume in the lateral orbitofrontal cortex was associated with a higher number of commission errors, possibly indicating that the dual mechanisms theory of PFC control was conceptually correct, but that a different PFC subregion than anticipated exerts control over commission errors. Collectively, the registered and post hoc analysis findings showed a functional dissociation across MTL/PFC regions that was more consistent with the dual mechanisms theory than the alternative theories.
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DOI：
--
发表时间：
2013
期刊：
Psychological Research
影响因子：
--
作者：
Moritz Walser;T. Goschke;Rico Fischer
通讯作者：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.1080/01688639108405107
发表时间：
1991-11-01
影响因子：
2.2
作者：
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通讯作者：
TRANEL, D
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DOI：
--
发表时间：
2014
期刊：
影响因子：
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作者：
Angel Muñoz Gómez Andrade
通讯作者：
Angel Muñoz Gómez Andrade
影响因子：
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作者：
Anderson, Francis T.;Einstein, Gilles O.
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