Functional aspects of the mucosal immune system.
Functional aspects of the mucosal immune system.
复制标题
粘膜免疫系统的功能方面。
DOI:
10.1007/0-387-33778-4_2
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发表时间:
2006
影响因子:
--
通讯作者:
Nagler-Anderson,Cathryn
中科院分区:
文献类型:
--
作者:
Nagler-Anderson,Cathryn
The mucosal immune system is faced with a daunting challenge. It must quickly and efFiciendy protect the epithelial barrier from invasion by microbes while avoiding a response to antigenic stimuli from the commensal bacteria or food proteins that constandy bombard it.^ It meets this challenge through tighdy controlled overlapping regulatory mechanisms brought about by specialized populations of B and T cells. When these control mechanisms go awry, luminal bacteria drive the chronic intestinal inflammatory response that characterizes inflammatory bowel disease. This review summarizes the unique features of mucosal lymphocytes that help prevent the inappropriate generation of an inflammatory response.
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影响因子:
4.4
作者:
J. G. Wilson;W. Wong;E. Murphy;P. Schur;D. Fearon
通讯作者:
J. G. Wilson;W. Wong;E. Murphy;P. Schur;D. Fearon
影响因子:
4.4
作者:
G. D. Ross;William J. Yount;M. Walport;J. Winfield;Charles J. Parker;C. Fuller;Ronald P. Taylor;B. Myones;Peter J. Lachmann
通讯作者:
G. D. Ross;William J. Yount;M. Walport;J. Winfield;Charles J. Parker;C. Fuller;Ronald P. Taylor;B. Myones;Peter J. Lachmann
影响因子:
4.4
作者:
J. Schifferli;Y. Ng;J. Estreicher;M. Walport
通讯作者:
M. Walport
影响因子:
15.3
作者:
Wilson, J G;Murphy, E E;Wong, W W;Klickstein, L B;Weis, J H;Fearon, D T
通讯作者:
Fearon, D T
DOI:
10.1073/pnas.82.22.7711
发表时间:
1985
影响因子:
11.1
作者:
Wong,WW;Klickstein,LB;Smith,JA;Weis,JH;Fearon,DT
通讯作者:
Fearon,DT