Modifying Alcohol Consumption to Reduce Obesity: A Randomized Controlled Feasibility Study of a Complex Community-based Intervention for Men.
Modifying Alcohol Consumption to Reduce Obesity: A Randomized Controlled Feasibility Study of a Complex Community-based Intervention for Men.
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DOI：
10.1093/alcalc/agx067
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发表时间：
2017-11-01
期刊：
影响因子：
--
通讯作者：
Allan S
中科院分区：
文献类型：
--
作者：
Irvine L;Crombie IK;Cunningham KB;Williams B;Sniehotta FF;Norrie J;Melson AJ;Jones C;Rice P;Slane PW;Achison M;McKenzie A;Dimova ED;Allan S
肥胖和每周饮酒超过 14 个单位的酒精会使男性患肝病的风险极高。这项研究评估了减少饮酒量试验的可行性。它测试了招募策略、干预参与度、保留率和研究可接受性。通过两种方法招募年龄 35-64 岁、每周饮酒量 > 21 单位且 BMI > 30 的男性：通过全科医生患者登记和社区外展。干预是通过面对面的会议进行的，随后是一系列短信。训练有素的外行人员（研究协调员）进行了面对面的会议。从基线开始对参与者进行了为期 5 个月的随访，以测量每周的饮酒量和体重指数。超过了 60 人的招募目标，共招募了 69 名男性并进行了随机分组。在基线时，几乎所有参与者 (95%) 都超过了死于肝病的风险增加 19 倍的阈值。干预以高保真度进行。达到了非常高的随访率（98%），并且测量了整个试验的结果。过程评估表明，参与者对行为改变策略中的关键步骤做出了预期的反应。研究方法的可接受性很高：例如80% 的男性会向其他人推荐这项研究。这项可行性研究确定了一群患有肝病的高风险人群。它表明可以进行全面的试验来测试干预措施的有效性和成本效益。当前对照试验：ISRCTN55309164。国家卫生研究院卫生技术评估 (NIHR HTA)。这项可行性研究招募了 69 名患有肝病高风险的男性。这种通过减肥动机来减少饮酒的新颖干预措施受到了好评。取得了非常高的随访率。过程评估表明参与者参与了行为改变策略的关键组成部分。
Being obese and drinking more than 14 units of alcohol per week places men at very high risk of developing liver disease. This study assessed the feasibility of a trial to reduce alcohol consumption. It tested the recruitment strategy, engagement with the intervention, retention and study acceptability. Men aged 35–64 years who drank >21 units of alcohol per week and had a BMI > 30 were recruited by two methods: from GP patient registers and by community outreach. The intervention was delivered by a face to face session followed by a series of text messages. Trained lay people (Study Coordinators) delivered the face to face session. Participants were followed up for 5 months from baseline to measure weekly alcohol consumption and BMI. The recruitment target of 60 was exceeded, with 69 men recruited and randomized. At baseline, almost all the participants (95%) exceeded the threshold for a 19-fold increase in the risk of dying from liver disease. The intervention was delivered with high fidelity. A very high follow-up rate was achieved (98%) and the outcomes for the full trial were measured. Process evaluation showed that participants responded as intended to key steps in the behaviour change strategy. The acceptability of the study methods was high: e.g. 80% of men would recommend the study to others. This feasibility study identified a group at high risk of liver disease. It showed that a full trial could be conducted to test the effectiveness and cost-effectiveness of the intervention. Current controlled trials: ISRCTN55309164. National Institute for Health Research Health Technology Assessment (NIHR HTA). This feasibility study recruited 69 men at high risk of developing liver disease. The novel intervention, to reduce alcohol consumption through the motivation of weight loss, was well received. A very high follow-up rate was achieved. Process evaluation showed that participants engaged with key components of the behaviour change strategy.
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影响因子：
2.8
作者：
Lloyd-Richardson, Elizabeth E;Lucero, Monica L;Wing, Rena R
通讯作者：
Wing, Rena R
影响因子：
105.7
作者：
Kaner, Eileen;Bland, Martin;Drummond, Colin
通讯作者：
Drummond, Colin
DOI：
10.1136/bmj.c1240
发表时间：
2010-03-11
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Hart CL;Morrison DS;Batty GD;Mitchell RJ;Davey Smith G
通讯作者：
Davey Smith G
影响因子：
2.9
作者：
Brueton, V. C.;Tierney, J. F.;Rait, G.
通讯作者：
Rait, G.
影响因子：
2.3
作者：
Borrelli B
通讯作者：
Borrelli B