Early intervention to reduce the global health and economic burden of major depression in older adults.

Early intervention to reduce the global health and economic burden of major depression in older adults.
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DOI:
10.1146/annurev-publhealth-031811-124544
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发表时间:
2012-04
影响因子:
20.8
通讯作者:
Albert SM
Albert SM
中科院分区:
医学1区
文献类型:
--
作者:
Reynolds CF 3rd;Cuijpers P;Patel V;Cohen A;Dias A;Chowdhary N;Okereke OI;Dew MA;Anderson SJ;Mazumdar S;Lotrich F;Albert SM

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在高收入国家(HIC)进行的混合年龄和老年人样本中选择性和指示性预防抑郁症的随机试验表明,通过使用旨在增加保护因素的心理教育和心理干预,抑郁症的发病率可以在1-2年内降低20-25%。重性抑郁症的复发也可以通过心理和精神药理学策略大大减少。然而,还需要更多的研究来解决中低收入国家(LMIC)老年人抑郁症预防的具体问题。全球老年人数量的不断增加,以及劳动力问题和干预费用,使得制定合理、有针对性且具有成本效益的风险降低策略变得重要。在我们看来,解决这些问题的一种策略是使用非专业健康顾问(LHC),这是一种已经被证明在治疗LMIC常见精神障碍方面有效的任务转移形式。我们建议在这篇评论中,时间是正确的研究转化为抑郁症预防策略用于中低收入国家。
Randomized trials for selective and indicated prevention of depression in both mixed-aged and older adult samples, conducted in high-income countries (HICs), show that rates of incident depression can be reduced by 20–25% over 1–2 years through the use of psychoeducational and psychological interventions designed to increase protective factors. Recurrence of major depression can also be substantially reduced through both psychological and psychopharmacological strategies. Additional research is needed, however, to address the specific issues of depression prevention in older adults in low- and middle-income countries (LMICs). The growing number of older adults globally, as well as work-force issues and the expense of interventions, makes it important to develop rational, targeted, and cost-effective risk-reduction strategies. In our opinion, one strategy to address these issues entails the use of lay health counselors (LHCs), a form of task shifting already shown to be effective in the treatment of common mental disorders in LMICs. We suggest in this review that the time is right for research into the translation of depression-prevention strategies for use in LMICs.
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