Biomechanical considerations in the pathogenesis of osteoarthritis of the knee.
Biomechanical considerations in the pathogenesis of osteoarthritis of the knee.
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DOI:
10.1007/s00167-011-1818-0
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发表时间:
2012-03
影响因子:
3.8
通讯作者:
Van Dijk, C. Niek
中科院分区:
文献类型:
--
作者:
Heijink, Andras;Gomoll, Andreas H.;Madry, Henning;Drobnic, Matej;Filardo, Giuseppe;Espregueira-Mendes, Joao;Van Dijk, C. Niek
Osteoarthritis is the most common joint disease and a major cause of disability. The knee is the large joint most affected. While chronological age is the single most important risk factor of osteoarthritis, the pathogenesis of knee osteoarthritis in the young patient is predominantly related to an unfavorable biomechanical environment at the joint. This results in mechanical demand that exceeds the ability of a joint to repair and maintain itself, predisposing the articular cartilage to premature degeneration. This review examines the available basic science, preclinical and clinical evidence regarding several such unfavorable biomechanical conditions about the knee: malalignment, loss of meniscal tissue, cartilage defects and joint instability or laxity. Level of evidence IV.
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DOI:
10.1115/1.3138409
发表时间:
1983-01-01
影响因子:
1.7
作者:
AHMED, AM;BURKE, DL
通讯作者:
BURKE, DL
影响因子:
7
作者:
Baliunas, AJ;Hurwitz, DE;Andriacchi, TP
通讯作者:
Andriacchi, TP
影响因子:
3.8
作者:
Becher, Christoph;Huber, Roland;Thermann, Hajo;Paessler, Hans H.;Skrbensky, Gobert
通讯作者:
Skrbensky, Gobert
影响因子:
2.8
作者:
ATHANASIOU, KA;ROSENWASSER, MP;MOW, VC
通讯作者:
MOW, VC
DOI:
10.1002/art.24466
发表时间:
2009-05-15
期刊:
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子:
--
作者:
Birmingham, Trevor B.;Giffin, J. Robert;Fowler, Peter J.
通讯作者:
Fowler, Peter J.