Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for research and clinical care.
Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for research and clinical care.
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DOI：
10.1016/j.ajog.2008.12.037
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发表时间：
2009-05
影响因子：
9.8
通讯作者：
Nieman, Lynnette K.
中科院分区：
文献类型：
--
作者：
Levens, Eric D.;Wesley, Robert;Premkumar, Ahalya;Blocker, Wendy;Nieman, Lynnette K.
为了比较MR和US成像用于子宫肌瘤测量，18名因症状性子宫肌瘤而接受子宫切除术的女性接受了术前盆腔US和MR成像。将切除的肌瘤与图像进行相关性分析。计算患者特征的加权kappa一致性统计和斯皮尔曼相关性。MR成像识别了151个经病理证实的肌瘤中的121个，阳性预测值（PPV）为91%（95%CI：85%，95%），敏感性为80%（95%CI：73%，86%）。超声的阳性预测值和敏感性分别为97%（95%CI：89%，100%）和40%（95%CI：32%，48%）。MRI和US的成像和病理测量之间的平均直径等效差异分别为0.51±0.68 cm和0.76±0.88 cm。比较成像与病理的Kappa统计显示MR的一致性优于US（k=0.60 vs. 0.36）。通过MR成像检测到的肌瘤数量预测了测量误差（r=0.76; p=0.0002）。上级灵敏度和最小的测量差异表明，MR成像应优先用于临床研究中评估肌瘤。
To compare MR and US imaging for uterine fibroid measurement Eighteen women undergoing hysterectomy for symptomatic fibroids underwent preoperative pelvic US and MR imaging. Resected fibroids were correlated with the images. Weighted kappa agreement statistics and Spearman correlations for patient characteristics were calculated. MR imaging identified 121 of 151 pathologically-confirmed fibroids, yielding 91% positive predictive value (PPV) (95%CI: 85%,95%) and 80% sensitivity (95%CI: 73%,86%). PPV and sensitivity for US were 97% (95%CI: 89%,100%) and 40% (95%CI: 32%,48%), respectively. Mean diameter-equivalent discrepancies between imaging and pathological measurements were 0.51±0.68 cm for MRI and 0.76±0.88 cm for US. Kappa statistics comparing imaging to pathology showed better agreement for MR than US (k=0.60 vs. 0.36). The number of fibroids detected by MR imaging predicted measurement errors (r=0.76; p=0.0002). Superior sensitivity and minimal measurement discrepancies suggest MR imaging should be preferentially utilized for assessing fibroids in clinical research studies.
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影响因子：
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