BMP signaling pathway and spinal cord development
BMP signaling pathway and spinal cord development
复制标题
BMP信号通路与脊髓发育
DOI:
10.1007/s11515-011-1178-7
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发表时间:
2012-01
期刊:
影响因子:
--
通讯作者:
Naihe Jing
中科院分区:
文献类型:
--
作者:
Zhihui Xie;Zhihui Xie;Naihe Jing;Naihe Jing
The development of spinal cord is a precisely and sequentially regulated process, which is controlled by signaling pathways and transcription factors in each stage. Overwhelming data have shown the essential roles of BMP signaling in different stages of this developmental process. It is also clear that the proper functions of BMP signaling require its cross-talk with several other signaling pathways including Notch, Wnt and retinoic acid (RA) pathways. Here, we highlight the recent advancement in understanding the roles of BMP signaling during neurogenesis, neural tube patterning, axon development and glial differentiation in the spinal cord, and emphasize its integrations with other pathways during these processes.
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