Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
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富含 PEST 结构域的酪氨酸磷酸酶在调节肥大细胞中抗原介导的糖皮质激素激活和抗过敏作用中的作用的转录组数据
DOI：
10.1016/j.dib.2018.08.188
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发表时间：
2018
期刊：
影响因子：
1.2
通讯作者：
Cato ACB
中科院分区：
文献类型：
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作者：
Ainooson GK;Gourain V;Stassen M;Cato ACB
蛋白酪氨酸磷酸酶和糖皮质激素调节激活的肥大细胞的过敏和抗过敏作用。在这里，我们提供了来自骨髓来源的肥大细胞的RNA测序和实时定量PCR数据，用于野生型和PEP结构域丰富的酪氨酸磷酸酶(PEP)缺失小鼠，由免疫球蛋白E敏化和二硝基苯酚处理激活，并附加糖皮质激素地塞米松治疗。转录转录实验一式两份，共16个样本(GSE108972)。
Protein tyrosine phosphatases and glucocorticoids are known to regulate allergic and antiallergic action in activated mast cells. Here we provide RNA sequencing and quantitative real-time PCR data from bone marrow derived mast cells, for wild-type and PEST-domain-enriched tyrosine phosphatase (PEP) null mice, activated by immunoglobulin E sensitization and dinitrophenol treatment, and additionally treated with the glucocorticoid dexamethasone. The transcriptomics experiment was performed in duplicate with a total of 16 samples (GSE108972).
DOI：
10.1093/bioinformatics/btu638
发表时间：
2015-01-15
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Anders S;Pyl PT;Huber W
通讯作者：
Huber W
影响因子：
12.4
作者：
Obiri, D. D.;Flink, N.;Cato, A. C. B.
通讯作者：
Cato, A. C. B.