A combination recombinant protein and outer membrane vesicle vaccine against serogroup B meningococcal disease

A combination recombinant protein and outer membrane vesicle vaccine against serogroup B meningococcal disease
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重组蛋白和外膜囊泡联合疫苗针对 B 群脑膜炎球菌病

DOI:
10.1586/erv.11.32
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发表时间:
2011
影响因子:
6.2
通讯作者:
M. Snape
M. Snape
中科院分区:
医学2区
文献类型:
--
作者:
E. Su;M. Snape

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虽然由血清群B引起的脑膜炎球菌病仍然是一个重要的公共卫生问题,但目前还没有一种获得许可的疫苗可广泛预防这种病原体。基因组学的进展为发现纳入多组分血清群B疫苗的新候选疫苗铺平了道路。在这篇文章中,我们将回顾这些疫苗的发展,特别是集中在“下一代”MenB疫苗,4CMenB的最新进展。
Although meningococcal disease caused by serogroup B remains an important public health concern, a licensed vaccine providing broad protection against this pathogen is not yet available. Advances in genomics have paved the way for the discovery of new vaccine candidates for inclusion into a multicomponent serogroup B vaccine. In this article, we will review recent advances in the development of these vaccines, focussing particularly on one of the ‘next generation’ MenB vaccines, 4CMenB.
DOI: 10.1073/pnas.0603940103
发表时间: 2006-07-18
影响因子: 11.1
作者:
Giuliani, Marzia M.;Adu-Bobie, Jeannette;Pizza, Mariagrazia
通讯作者: Pizza, Mariagrazia
DOI: 10.1086/648966
发表时间: 2010-03-01
期刊: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子: --
作者:
Granoff DM
通讯作者: Granoff DM