Association of e-Cigarette Use With Discontinuation of Cigarette Smoking Among Adult Smokers Who Were Initially Never Planning to Quit.
Association of e-Cigarette Use With Discontinuation of Cigarette Smoking Among Adult Smokers Who Were Initially Never Planning to Quit.
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DOI：
10.1001/jamanetworkopen.2021.40880
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发表时间：
2021-12-01
影响因子：
13.8
通讯作者：
Hyland A
中科院分区：
文献类型：
--
作者：
Kasza KA;Edwards KC;Kimmel HL;Anesetti-Rothermel A;Cummings KM;Niaura RS;Sharma A;Ellis EM;Jackson R;Blanco C;Silveira ML;Hatsukami DK;Hyland A
在最初不打算戒烟的吸烟者中，电子烟的使用是否与停止使用香烟有关？在这项具有美国全国代表性的队列研究中，1600名成年每日吸烟者最初不使用电子烟，也没有戒烟计划，随后每天使用电子烟与戒烟几率显著相关，是不使用电子烟的8倍。这些发现呼吁在评估电子烟在人群中戒烟的风险和益处潜力时考虑不打算戒烟的吸烟者。这项队列研究评估了电子烟的使用是否与美国成年吸烟者停止吸烟有关，这些吸烟者最初从未打算戒烟。在评估电子尼古丁递送产品(电子烟)的风险-收益潜力的人口研究中，不打算戒烟的吸烟者往往被忽视。评估电子烟的使用是否与最初从未打算戒烟的吸烟者停止吸烟有关。这项队列研究使用了美国全国具有代表性的数据，来自烟草与健康纵向人口评估研究(在2014年10月至2019年11月期间进行的第2至第5波)，参与者在3对访谈中进行了评估。成年的日常吸烟者最初不使用电子烟，也没有永久戒烟的计划(1600人的2489次观察)被纳入其中。在基线访谈中对不使用电子烟的吸烟者进行跟踪访谈时的电子烟使用情况(即日常使用、非日常使用或不使用)。主要结果是在随访时停止吸烟(即不吸烟)和停止日常吸烟(即不每天吸烟)。使用广义估计方程来评估暴露与每个结果之间的关联，控制人口统计特征和基线访谈中每天吸烟；所有估计都是加权的。根据1600名参与者的数据，不使用电子烟且没有戒烟计划的成年日常吸烟者的加权人口为56.1%的男性(95%CI，53.4%-58.7%)，10.1%的西班牙裔(95%CI，8.2%-12.3%)，10.1%的非西班牙裔黑人(95%CI，8.7%-11.7%)，75.6%的非西班牙裔白人(95%CI，72.9%-78.2%)，非西班牙裔占4.2%(95%CI，3.3%~5.4%)；29.3%的人年龄在55-69岁之间(95%CI，26.2%-32.6%)，8.9%的人年龄在70岁以上(95%CI，6.8%-11.5%)，36.8%的人没有高中毕业(95%CI，341%-39.6%)，55.2%的家庭年收入低于25 000美元(95%CI，52.3%-581%)，37.6%的人每天吸烟20-29支(95%CI，34.7%~40.6%)，每天吸烟30支以上的占12.7%(95%CI，10.9%~14.7%)。总体而言，6.2%的人口(95%可信区间，5.0%-7.5%)戒烟。每天使用电子烟的人的戒烟率(28.0%；95%可信区间，15.2%-45.9%)高于从不使用电子烟的人群(5.8%；95%可信区间，4.7%-7.2%；调整后的优势比[AOR]，8.11；95%可信区间，3.14-20.97)。此外，10.7%(95%可信区间，9.1%~12.5%)的人每天停止吸烟，每天使用电子烟的人群戒烟率(45.5%；95%可信区间，27.4%~64.9%)高于从不使用电子烟的人群(9.9%；95%可信区间，8.2%~11.8%；AOR，9.67；95%可信区间，4.02~23.25)。非每日使用电子烟与停止吸烟(AOR，0.53；95%CI，0.08-3.35)或每天停止吸烟(AOR，0.96；95%CI，0.44-2.09)无关。在这项队列研究中，在最初没有戒烟计划的吸烟者中，每天使用电子烟与更大的戒烟几率有关。这些发现支持在评估电子烟在人群中戒烟的风险和益处潜力时，考虑不打算戒烟的吸烟者。
Is e-cigarette use associated with discontinuation of cigarette use among smokers initially not planning to ever quit? In this US nationally representative cohort study of 1600 adult daily cigarette smokers who did not initially use e-cigarettes and had no plans to ever quit smoking, subsequent daily e-cigarette use was significantly associated with an 8-fold greater odds of cigarette discontinuation compared with no e-cigarette use. These findings call for consideration of smokers who are not planning to quit when evaluating the risk-benefit potential of e-cigarettes for smoking cessation in the population. This cohort study evaluates whether e-cigarette use is associated with the discontinuation of cigarette smoking among US adult smokers who were initially never planning to quit. Cigarette smokers not planning to quit are often overlooked in population studies evaluating the risk-benefit potential of electronic nicotine delivery products (e-cigarettes). To evaluate whether e-cigarette use is associated with discontinuing cigarette smoking among smokers who were initially never planning to quit. This cohort study used US nationally representative data from the longitudinal Population Assessment of Tobacco and Health Study (waves 2-5 conducted between October 2014 and November 2019), with participants evaluated in 3 pairs of interviews. Adult daily cigarette smokers initially not using e-cigarettes and with no plans to ever quit smoking for good (2489 observations from 1600 individuals) were included. e-Cigarette use (ie, daily use, nondaily use, or no use) at follow-up interview among smokers not using e-cigarettes at baseline interview. The main outcomes were discontinuation of cigarette smoking (ie, no cigarette smoking) and discontinuation of daily cigarette smoking (ie, no daily cigarette smoking) at follow-up interview. Generalized estimating equations were used to evaluate the association between the exposure and each outcome, controlling for demographic characteristics and cigarettes smoked per day at baseline interview; all estimates were weighted. The weighted population of adult daily cigarette smokers who were not using e-cigarettes and had no plans to ever quit smoking, based on data from 1600 participants, was 56.1% male (95% CI, 53.4%-58.7%), 10.1% Hispanic (95% CI, 8.2%-12.3%), 10.1% non-Hispanic Black (95% CI, 8.7%-11.7%), 75.6% non-Hispanic White (95% CI, 72.9%-78.2%), and 4.2% of other non-Hispanic race (95% CI, 3.3%-5.4%); 29.3% were aged 55 to 69 years (95% CI, 26.2%-32.6%), 8.9% were aged 70 years or older (95% CI, 6.8%-11.5%), 36.8% did not graduate from high school (95% CI, 34.1%-39.6%), 55.2% had an annual household income of less than $25 000 (95% CI, 52.3%-58.1%), 37.6% smoked 20 to 29 cigarettes per day (95% CI, 34.7%-40.6%), and 12.7% smoked 30 or more cigarettes per day (95% CI, 10.9%-14.7%). Overall, 6.2% of the population (95% CI, 5.0%-7.5%) discontinued cigarette smoking. Discontinuation rates were higher among those who used e-cigarettes daily (28.0%; 95% CI, 15.2%-45.9%) compared with not at all (5.8%; 95% CI, 4.7%-7.2%; adjusted odds ratio [aOR], 8.11; 95% CI, 3.14-20.97). Furthermore, 10.7% (95% CI, 9.1%-12.5%) discontinued daily cigarette smoking, with higher rates of discontinuation observed among those who used e-cigarettes daily (45.5%; 95% CI, 27.4%-64.9%) compared with not at all (9.9%; 95% CI, 8.2%-11.8%; aOR, 9.67; 95% CI, 4.02-23.25). Nondaily e-cigarette use was not associated with cigarette discontinuation (aOR, 0.53; 95% CI, 0.08-3.35) or daily cigarette discontinuation (aOR, 0.96; 95% CI, 0.44-2.09). In this cohort study, daily e-cigarette use was associated with greater odds of cigarette discontinuation among smokers who initially had no plans to ever quit smoking. These findings support the consideration of smokers who are not planning to quit when evaluating the risk-benefit potential of e-cigarettes for smoking cessation in the population.
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影响因子：
4.4
作者：
Asfar, Taghrid;Ebbert, Jon O.;Klesges, Robert C.;Relyea, George E.
通讯作者：
Relyea, George E.
DOI：
10.1056/nejmsa1607538
发表时间：
2017-01-26
期刊：
The New England journal of medicine
影响因子：
--
作者：
Kasza KA;Ambrose BK;Conway KP;Borek N;Taylor K;Goniewicz ML;Cummings KM;Sharma E;Pearson JL;Green VR;Kaufman AR;Bansal-Travers M;Travers MJ;Kwan J;Tworek C;Cheng YC;Yang L;Pharris-Ciurej N;van Bemmel DM;Backinger CL;Compton WM;Hyland AJ
通讯作者：
Hyland AJ
影响因子：
5.2
作者：
Hyland, Andrew;Ambrose, Bridget K.;Compton, Wilson M.
通讯作者：
Compton, Wilson M.
影响因子：
12.7
作者：
Wang, Richard J.;Bhadriraju, Sudhamayi;Glantz, Stanton A.
通讯作者：
Glantz, Stanton A.
影响因子：
4.2
作者：
Hughes, John R.;Solomon, Laura J.;Callas, Peter W.
通讯作者：
Callas, Peter W.