The basal ganglia is necessary for learning spectral, but not temporal, features of birdsong.
The basal ganglia is necessary for learning spectral, but not temporal, features of birdsong.
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DOI:
10.1016/j.neuron.2013.07.049
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发表时间:
2013-10-16
期刊:
影响因子:
16.2
通讯作者:
Ölveczky BP
中科院分区:
文献类型:
--
作者:
Ali F;Otchy TM;Pehlevan C;Fantana AL;Burak Y;Ölveczky BP
Executing a motor skill requires the brain to control which muscles to activate at what times. How these aspects of control - motor implementation and timing - are acquired, and whether the learning processes underlying them differ, is not well understood. To address this we used a reinforcement learning paradigm to independently manipulate both spectral and temporal features of birdsong, a complex learned motor sequence, while recording and perturbing activity in underlying circuits. Our results uncovered a striking dissociation in how neural circuits underlie learning in the two domains. The basal ganglia was required for modifying spectral, but not temporal structure. This functional dissociation extended to the descending motor pathway, where recordings from a premotor cortex analogue nucleus reflected changes to temporal, but not spectral structure. Our results reveal a strategy in which the nervous system employs different and largely independent circuits to learn distinct aspects of a motor skill.
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