Tele-Interpersonal Psychotherapy Acutely Reduces Depressive Symptoms in Depressed HIV-Infected Rural Persons: A Randomized Clinical Trial.
Tele-Interpersonal Psychotherapy Acutely Reduces Depressive Symptoms in Depressed HIV-Infected Rural Persons: A Randomized Clinical Trial.
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DOI：
10.1080/08964289.2016.1160025
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发表时间：
2017-10
期刊：
影响因子：
--
通讯作者：
Sutton M
中科院分区：
文献类型：
--
作者：
Heckman TG;Heckman BD;Anderson T;Lovejoy TI;Markowitz JC;Shen Y;Sutton M
艾滋病毒阳性的农村人群患抑郁症的风险是城市人群的1.3倍。这项随机临床试验测试了来自28个州的132名被诊断为DSM-IV型重度抑郁症（MDD）、部分缓解MDD或心境恶劣症的hiv感染者的电话人际心理治疗（tele-IPT）是否能急性缓解抑郁症状。患者被随机分配到9次一对一远程ipt （n=70）或标准治疗（n= 62）。一系列治疗意向（ITT）、治疗完成率和敏感性分析评估了干预前后抑郁症状、人际关系问题和社会支持的变化。在所有分析中，远程ipt患者报告的抑郁症状和人际关系问题明显低于SC对照组；在ITT分析中，22%的远程ipt患者被归类为先验的“应答者”，他们报告抑郁症状减轻≥50%，而SC对照组只有4%。简短的远程ipt能显著降低农村艾滋病毒感染者的抑郁症状和人际关系问题。
HIV-positive rural individuals carry a 1.3 times greater risk of a depressive diagnosis than their urban counterparts. This randomized clinical trial tested whether telephone-administered interpersonal psychotherapy (tele-IPT) acutely relieved depressive symptoms in 132 HIV-infected rural persons from 28 states diagnosed with DSM-IV Major Depressive Disorder (MDD), partially remitted MDD, or Dysthymic Disorder. Patients were randomized to either 9 sessions of one-on-one tele-IPT (n=70) or standard care (SC; n=62). A series of intent-to-treat (ITT), therapy completer, and sensitivity analyses assessed changes in depressive symptoms, interpersonal problems, and social support from pre- through post-intervention. Across all analyses, tele-IPT patients reported significantly lower depressive symptoms and interpersonal problems than SC controls; 22% of tele-IPT patients were categorized as a priori “responders” who reported ≥50% reductions in depressive symptoms compared to only 4% of SC controls in ITT analyses. Brief tele-IPT acutely decreased depressive symptoms and interpersonal problems in depressed rural people living with HIV.
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