Cellular Diversity and Regeneration in Taste Buds.

Cellular Diversity and Regeneration in Taste Buds.
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DOI:
10.1016/j.cophys.2021.01.003
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发表时间:
2021-04
影响因子:
2.5
通讯作者:
Barlow LA
Barlow LA
中科院分区:
其他
文献类型:
--
作者:
Finger TE;Barlow LA

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味蕾是味觉的感觉末端器官,介导咸、酸、苦、甜和鲜味以及其他可能的形式,例如脂肪和厚味的感觉。在过去的几十年里,随着超微结构方法、分子遗传学和体外模型的进步,对这些感觉器官的结构和功能的理解大大增加。本文就味蕾的细胞组成及味蕾细胞更新和分化的分子调控作一综述。
Taste buds are the sensory end organs for gustation, mediating sensations of salty, sour, bitter, sweet and umami as well as other possible modalities, e.g. fat and kokumi. Understanding of the structure and function of these sensory organs has increased greatly in the last decades with advances in ultrastructural methods, molecular genetics, and in vitro models. This review will focus on the cellular constituents of taste buds, and molecular regulation of taste bud cell renewal and differentiation.
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