The role of the amygdala and dorsal raphe nucleus in mediating the behavioral consequences of inescapable shock.
The role of the amygdala and dorsal raphe nucleus in mediating the behavioral consequences of inescapable shock.
复制标题
杏仁核和中缝背核在调节不可避免的休克的行为后果中的作用。
DOI:
10.1037//0735-7044.107.2.377
复制
发表时间:
1993
影响因子:
1.9
通讯作者:
Watkins,LR
中科院分区:
文献类型:
--
作者:
Maier,SF;Grahn,RE;Kalman,BA;Sutton,LC;Wiertelak,EP;Watkins,LR
It has been argued that exposure to inescapable shock produces later behavioral changes such as poor shuttle box escape learning because it leads to the conditioning of intense fear, which later transfers to the shuttle box test situation and interferes with escape. Both fear, as assessed by freezing, and escape were measured in Sprague-Dawley rats 24 hrs after exposure to inescapable shock. Lesions of the basolateral region and central nucleus of the amygdala eliminated the fear that transfers to the shuttle box after inescapable shock, as well as the fear conditioned in the shuttle box by the shuttle box shocks. However, the amygdala lesions did not reduce the learning deficit produced by inescapable shock. In contrast, dorsal raphe nucleus lesions did not reduce the fear that transfers to the shuttle box after inescapable shock, but eliminated the enhanced fear conditioning in the shuttle box as well as the escape deficit. The implications of these results for the role of fear and anxiety in mediating inescapable shock effects are discussed.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
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影响因子:
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作者:
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通讯作者:
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影响因子:
2.9
作者:
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D. German
DOI:
--
发表时间:
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期刊:
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作者:
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通讯作者:
REIS, DJ
DOI:
--
发表时间:
1991
期刊:
影响因子:
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作者:
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通讯作者:
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