CFD Simulation and Experimental Validation of Fluid Flow and Particle Transport in a Model of Alveolated Airways.
CFD Simulation and Experimental Validation of Fluid Flow and Particle Transport in a Model of Alveolated Airways.
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DOI：
10.1016/j.jaerosci.2009.01.002
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发表时间：
2009-05
影响因子：
4.5
通讯作者：
Darquenne, Chantal
中科院分区：
文献类型：
--
作者：
Ma, Baoshun;Ruwet, Vincent;Corieri, Patricia;Theunissen, Raf;Riethmuller, Michel;Darquenne, Chantal
Accurate modeling of air flow and aerosol transport in the alveolated airways is essential for quantitative predictions of pulmonary aerosol deposition. However, experimental validation of such modeling studies has been scarce. The objective of this study is to validate CFD predictions of flow field and particle trajectory with experiments within a scaled-up model of alveolated airways. Steady flow (Re = 0.13) of silicone oil was captured by particle image velocimetry (PIV), and the trajectories of 0.5 mm and 1.2 mm spherical iron beads (representing 0.7 to 14.6 μm aerosol in vivo) were obtained by particle tracking velocimetry (PTV). At twelve selected cross sections, the velocity profiles obtained by CFD matched well with those by PIV (within 1.7% on average). The CFD predicted trajectories also matched well with PTV experiments. These results showed that air flow and aerosol transport in models of human alveolated airways can be simulated by CFD techniques with reasonable accuracy.
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DOI：
10.1115/1.1784476
发表时间：
2004-08-01
影响因子：
1.7
作者：
Karl, A;Henry, FS;Tsuda, A
通讯作者：
Tsuda, A
影响因子：
3.7
作者：
Kim, I;Elghobashi, S;Sirignano, WA
通讯作者：
Sirignano, WA
影响因子：
3.3
作者：
DARQUENNE, C;PAIVA, M
通讯作者：
PAIVA, M
DOI：
10.1080/15298668091424933
发表时间：
1980-01-01
期刊：
AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL
影响因子：
--
作者：
STAHLHOFEN, W
通讯作者：
STAHLHOFEN, W
影响因子：
2.1
作者：
Oldham, Michael J.
通讯作者：
Oldham, Michael J.