Characteristics of false-positive lesions in evaluating colorectal liver metastases on gadoxetic acid-enhanced magnetic resonance imaging

Characteristics of false-positive lesions in evaluating colorectal liver metastases on gadoxetic acid-enhanced magnetic resonance imaging
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钆塞酸增强磁共振成像评估结直肠肝转移假阳性病灶特征

DOI:
10.1007/s00595-022-02451-5
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发表时间:
2022
期刊:
影响因子:
2.5
通讯作者:
Shimada Kazuaki
Shimada Kazuaki
中科院分区:
医学4区
文献类型:
--
作者:
Yamada Shuhei;Kishi Yoji;Miyake Mototaka;Nara Satoshi;Esaki Minoru;Shimada Kazuaki

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目的:Gd-EOB-MRI对结直肠癌肝转移的敏感性高于CT。然而,每个成像models. MethodsCase假阳性病变的细节进行肝切除术CRLM的术前评估与CECT和Gd-EOB-MRI之间2008年7月和2016年12月进行了审查。假阳性和假阴性率进行了评估,为每一种方式,假阳性病变的特点进行了evaluated.ResultsWe评估275部分肝切除术242例术前化疗。在275例肝切除术中,546个病灶被CECT和/或Gd-EOB-MRI识别。CECT和Gd-EOB-MRI的假阳性率分别为4%(18/422)和7%(37/536)。假阳性病灶的大小明显小于正确诊断病灶的大小(中位数:28 mm [3-120 mm] vs 7.6 mm [320 mm],P< 0.001)。与233个直径≤ 20 mm的病灶相比,位于肝表面或血管纤毛结构附近的假阳性病灶多于位于肝实质的病灶(分别为33/37 [89%] vs 149/233 [64%];P= 0.0021)。肿瘤体积小、位于体表或血管纤毛结构附近与假阳性相关。
PurposeGadoxetic acid-enhanced MRI (Gd-EOB-MRI) shows higher sensitivity for colorectal liver metastases (CRLM) than contrast-enhanced computed tomography (CECT). However, the details of false-positive lesions for each imaging modality are unknown.MethodsCases undergoing hepatectomy for CRLM following a preoperative evaluation with both CECT and Gd-EOB-MRI between July 2008 and December 2016 were reviewed. The false-positive and false-negative rates were assessed for each modality, and the characteristics of false-positive lesions were evaluated.ResultsWe evaluated 275 partial hepatectomies in 242 patients without preoperative chemotherapy. Among the 275 hepatectomies, 546 lesions were recognized by CECT and/or Gd-EOB-MRI. The false-positive rates for CECT and Gd-EOB-MRI were 4% (18/422) and 7% (37/536), respectively. The size of false-positive lesions was significantly smaller than that of correctly diagnosed lesions (median: 28 mm [3–120 mm] vs 7.6 mm [320 mm],P< 0.001). Compared with the 233 correctly diagnosed lesions ≤ 20 mm in diameter, false-positive lesions were more frequently located near the liver surface or vasculobiliary structures than true lesions (33/37 [89%] vs 149/233 [64%], respectively;P= 0.0021).ConclusionGd-EOB-MRI had a 7% false-positive rate. A small size and tumor location near the surface or near vasculobiliary structures were associated with false positivity.
DOI: 10.1097/00000658-199909000-00004
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