Abnormalities in the processing of emotional prosody from single words in schizophrenia.
Abnormalities in the processing of emotional prosody from single words in schizophrenia.
复制标题
精神分裂症患者对单个单词的情感韵律处理异常
DOI：
10.1016/j.schres.2013.10.042
复制
发表时间：
2014-01
影响因子：
4.5
通讯作者：
Niznikiewicz MA
中科院分区：
文献类型：
--
作者：
Pinheiro AP;Rezaii N;Rauber A;Liu T;Nestor PG;McCarley RW;Gonçalves OF;Niznikiewicz MA
在精神分裂症中，情绪韵律处理的异常一直被报道，并与不良的社会结果有关。然而，刺激复杂性在异常情绪韵律加工中的作用尚不清楚。本研究采用事件相关电位技术，对16名慢性精神分裂症患者和16名健康对照者进行了研究，目的是：1）情绪韵律加工的时间进程; 2）韵律线索和语义线索在情绪韵律加工中的相对贡献。刺激是在两种条件下呈现的韵律单词：可理解的（语义内容条件-SCC）和不可理解的语义内容（纯韵律条件-PPC）。相对于健康对照组，精神分裂症患者表现出减少P50快乐PPC的话，减少中性和情绪SCC的话和中性PPC刺激的N100。此外，增加P200观察到精神分裂症的快乐韵律在SCC。行为结果显示，较高的错误率在精神分裂症的愤怒韵律在SCC和快乐的韵律在PPC。总之，这些数据进一步证明了异常感觉过程和高阶过程之间的相互作用，导致精神分裂症患者的情绪韵律处理功能障碍。他们进一步表明，受损的情绪韵律处理依赖于刺激的复杂性。
Abnormalities in emotional prosody processing have been consistently reported in schizophrenia and are related to poor social outcomes. However, the role of stimulus complexity in abnormal emotional prosody processing is still unclear. We recorded event-related potentials in 16 patients with chronic schizophrenia and 16 healthy controls to investigate: 1) the temporal course of emotional prosody processing; 2) the relative contribution of prosodic and semantic cues in emotional prosody processing. Stimuli were prosodic single words presented in two conditions: with intelligible (semantic content condition–SCC) and unintelligible semantic content (pure prosody condition–PPC). Relative to healthy controls, schizophrenia patients showed reduced P50 for happy PPC words, and reduced N100 for both neutral and emotional SCC words and for neutral PPC stimuli. Also, increased P200 was observed in schizophrenia for happy prosody in SCC only. Behavioral results revealed higher error rates in schizophrenia for angry prosody in SCC and for happy prosody in PPC. Together, these data further demonstrate the interactions between abnormal sensory processes and higher-order processes in bringing about emotional prosody processing dysfunction in schizophrenia. They further suggest that impaired emotional prosody processing is dependent on stimulus complexity.
登录
查看更多内容
影响因子：
4.5
作者：
Edwards, Jane;Pattison, Philippa E.;Wales, Roger J.
通讯作者：
Wales, Roger J.
影响因子：
4.7
作者：
Godey, B;Schwartz, D;Liégeois-Chauvel, C
通讯作者：
Liégeois-Chauvel, C
影响因子：
6.6
作者：
Couture, Shannon M.;Penn, David L.;Roberts, David L.
通讯作者：
Roberts, David L.
影响因子：
11.3
作者：
Boutros, NN;Korzyukov, O;Bell, M
通讯作者：
Bell, M
影响因子：
6.6
作者：
Horan, William P.;Green, Michael F.;Nuechterlein, Keith H.
通讯作者：
Nuechterlein, Keith H.