Effect of Protein and Mechanical Strain on the Corrosion Resistance and Cytotoxicity of the Orthodontic Composite Arch Wire

Effect of Protein and Mechanical Strain on the Corrosion Resistance and Cytotoxicity of the Orthodontic Composite Arch Wire
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蛋白质和机械应变对正畸复合弓丝耐腐蚀性和细胞毒性的影响

DOI:
10.1021/acsomega.0c00803
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发表时间:
2020-04
期刊:
影响因子:
4.1
通讯作者:
Zhang Chao
Zhang Chao
中科院分区:
化学3区
文献类型:
--
作者:
He Longwen;Cui Ye;Zhang Chao

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本研究研究了不同类型唾液蛋白(纤维蛋白原、IgG和粘蛋白)暴露和体外弯曲应变对激光焊接正畸复合弓丝(CAW)的影响,并研究了其体外腐蚀行为和细胞毒性。目的是通过模拟临床应用,确定蛋白质暴露和弯曲载荷单独或联合导致CAW腐蚀的机制。结果表明,机械应变的施加显著降低了CAW的耐蚀性,增加了有毒腐蚀产物的释放。蛋白质的加入抑制了CAW的腐蚀,但机械载荷抵消了这种作用。粘蛋白增强了CAW的耐腐蚀性。在异质合金医用材料的应用中,应考虑蛋白质或菌种单独或联合作用的影响。
In this study, the effects of the exposure to different types of salivary proteins (fibrinogen, IgG, and mucin) and application of an in vitro bending strain on the laser welding orthodontic composite arch wire (CAW) were investigated, and the resultant corrosion behavior and cytotoxicity were studied in vitro. The purpose was to determine the mechanisms by which protein exposure and bending loads contribute to the corrosion of the CAW either alone or in combination by mimicking the clinical application. The results showed that the application of a mechanical strain significantly decreased the corrosion resistance of the CAW and increased the release of toxic corrosion products. The addition of the proteins inhibited the corrosion of the CAW, but the mechanical loads counteracted this effect. Mucin enhanced the corrosion resistance of the CAW. The effects of the proteins or strain, either alone or in combination, should be considered in the application of medical materials of heterogenetic alloys.
DOI: 10.1002/jbm.b.33097
发表时间: 2014-08-01
影响因子: 3.4
作者:
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