Towards an understanding of radiation damage in cryocooled macromolecular crystals.

Towards an understanding of radiation damage in cryocooled macromolecular crystals.
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了解低温冷却大分子晶体的辐射损伤。

DOI:
10.1107/s0909049505007132
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发表时间:
2005
影响因子:
2.5
通讯作者:
E. Garman
E. Garman
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
C. Nave;E. Garman

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Interest in radiation damage is growing rapidly owing to the surge in macromolecular crystallography experiments carried out at modern brilliant synchrotron macromolecular crystallography beamlines. Work on the characterization of radiation damage in cryocooled protein crystals is starting to have some impact on our understanding of the problem and of how damage might be affecting both the process of structure solution and the actual structure obtained. A brief review of the most recent developments is given together with an assessment of the remaining problems. Although progress is being made, the understanding of radiation damage is far from complete. Methods for recognizing the damage and treating the data are being made available but they are still at an early stage of development.
预测蛋白质晶体的 X 射线寿命。
DOI: 10.1073/pnas.1315879110
发表时间: 2013
影响因子: 11.1
作者:
Zeldin,OliverB;Brockhauser,Sandor;Bremridge,John;Holton,JamesM;Garman,ElspethF
通讯作者: Garman,ElspethF
DOI: 10.1016/s0969-2126(03)00006-6
发表时间: 2003-02-01
期刊: STRUCTURE
影响因子: 5.7
作者:
Ravelli, RBG;Leiros, HKS;McSweeney, S
通讯作者: McSweeney, S