Advances in the Treatment of Pediatric Brain Tumors.

Advances in the Treatment of Pediatric Brain Tumors.
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DOI:
10.3390/children10010062
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发表时间:
2022-12-27
期刊:
影响因子:
2.4
通讯作者:
Edwards, Michael S. B.
Edwards, Michael S. B.
中科院分区:
医学4区
文献类型:
--
作者:
Kulubya, Edwin S.;Kercher, Matthew J.;Phillips, H. Westley;Antony, Reuben;Edwards, Michael S. B.

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儿童脑肿瘤是儿童中最常见的实体恶性肿瘤。儿科脑肿瘤治疗的进展表现在成像、活检、手术技术和分子分析等方面。这为靶向治疗和免疫治疗在最常见类型的儿科脑肿瘤的临床试验中进行评估开辟了道路。在这里,我们回顾了靶向分子治疗,免疫治疗和较新的模式,如激光间质热治疗的最新努力和挑战。
Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.
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