Use of an implanted sacral nerve stimulator to restore urine voiding in chronically paraplegic dogs.
Use of an implanted sacral nerve stimulator to restore urine voiding in chronically paraplegic dogs.
复制标题
使用植入的骶神经刺激器来恢复慢性截瘫狗的排尿能力。
DOI：
10.1111/jvim.12011
复制
发表时间：
2013
影响因子：
2.6
通讯作者：
Granger N
中科院分区：
文献类型：
--
作者：
Granger N
BackgroundLoss of urinary control after spinal cord injury increases risk of urinary tract disease and is problematic for owners of affected dogs.ObjectivesTo design，implant，and test a sacral nerve stimulating device for controlling urine voiding in paraplegic dogs.AnimalsNine pet dogs with severe thoracolumbar spinal cord injury causing paraplegia，loss of hindquarter sensation，and incontinence for more than 3 months.该程序提供了前瞻性的业主合适的候选人后，尿失禁的不可逆性已被determined.MethodsOpen标签临床研究。手术植入电极“书”的目的是插入和保留混合骶神经。骶神经通过椎板切除术和刺激，以测试他们的能力，引起逼尿肌收缩，然后插入到电极书，这是附加到一个皮下植入，外部激活receiver.ResultsIn 8/9狗，S2神经引起最大的膀胱内压力增加最小的刺激，并被放置在电极书。9只植入犬中有8只的排尿效率>90%。没有重要的有害影响的程序observed.Conclusions和临床ImportanceThis骶神经刺激植入物是一个简单的，显然有效的神经假体装置，恢复截瘫犬排尿。
BackgroundLoss of urinary control after spinal cord injury increases risk of urinary tract disease and is problematical for owners of affected dogs.ObjectivesTo design, implant, and test a sacral nerve stimulating device for controlling urine voiding in paraplegic dogs.AnimalsNine pet dogs with severe thoracolumbar spinal cord injury causing paraplegia, loss of hindquarter sensation, and incontinence for more than 3 months. The procedure was offered prospectively to owners of suitable candidates after the irreversibility of the incontinence had been ascertained.MethodsOpen label clinical study. Surgically implantable electrode “books” were designed for insertion and retention of mixed sacral nerves. Sacral nerves were accessed via laminectomy and stimulated to test their ability to elicit detrusor contraction and then inserted into the electrode book, which was attached to a subcutaneously implanted, externally activated receiver.ResultsIn 8/9 dogs, S2 nerves elicited the largest increases in intravesicular pressure with minimum stimulation and were placed in electrode books. Voiding efficiency was >90% in 8 of the 9 implanted dogs. No important detrimental effects of the procedure were observed.Conclusions and Clinical ImportanceThis sacral nerve stimulating implant is a simple and apparently effective neuroprosthetic device that restores urine voiding in paraplegic dogs.
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影响因子：
1.4
作者：
Martens FM;Heesakkers JP
通讯作者：
Heesakkers JP
第 1 章 – 神经病史、神经解剖学和神经系统检查
DOI：
--
发表时间：
2011
期刊：
影响因子：
--
作者：
M. Lorenz
通讯作者：
M. Lorenz
兽医神经病学手册
DOI：
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发表时间：
1993
期刊：
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--
作者：
Oliver Je;M. Lorenz;J. Kornegay
通讯作者：
J. Kornegay
使用自行设计的膀胱控制器恢复截瘫犬的膀胱功能。
DOI：
--
发表时间：
2003
期刊：
Chinese journal of traumatology = Zhonghua chuang shang za zhi
影响因子：
--
作者：
Shi;C. Hou;Ying;Ai;Shimin Zhang;Bo Lei;Cheng;Wei Zhang
通讯作者：
Wei Zhang
DOI：
10.1109/86.895949
发表时间：
2000-12-01
期刊：
IEEE TRANSACTIONS ON REHABILITATION ENGINEERING
影响因子：
--
作者：
Boyer, S;Sawan, M;Elhilali, MM
通讯作者：
Elhilali, MM