Design and implementation of a prototype head and neck phantom for the performance evaluation of gamma imaging systems.
Design and implementation of a prototype head and neck phantom for the performance evaluation of gamma imaging systems.
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DOI：
10.1186/s40658-017-0186-3
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发表时间：
2017-12
期刊：
影响因子：
4
通讯作者：
Perkins AC
中科院分区：
文献类型：
--
作者：
Alqahtani MS;Lees JE;Bugby SL;Samara-Ratna P;Ng AH;Perkins AC
设计了一个原型拟人头颈体模，用于模拟成人头颈解剖结构，包括一些感兴趣的内脏器官和组织，如甲状腺和前哨淋巴结（SLN）。头颈部体模的设计包括一个固定模拟SLN和甲状腺的内部夹具。甲状腺结构是使用三维（3D）打印制造的，考虑到健康成人甲状腺的形态和形状。采用头颈部体模模拟了四个SLN分布在颈部两个不同垂直高度和两个深度的情况。对比度噪声比（CNR）的计算进行了检测的SLN之间的针孔准直器（0.5和1.0 mm直径）和头部和颈部体模的表面与100 s的采集时间为80 mm的距离。当混合伽马相机（HGC）配备有1.0 mm直径针孔准直器时，模拟SLN的CNR值较高。例如，使用0.5 mm和1.0 mm直径针孔准直器记录的含有0.1 MBq 99 mTc的表面模拟SLN（15 mm深度）的CNR值分别为6.48和16.42（差异约为87%）。使用HGC采集模拟甲状腺的伽马和混合光学图像。通过两个针孔准直器提供的模拟甲状腺图像的中间获得计数曲线。在0.5 mm针孔准直器产生的伽玛图像中，HGC可以清楚地区分两个甲状腺叶的各个峰。相比之下，使用1.0 mm直径针孔准直器采集图像的记录计数曲线显示两个瓣的峰值更宽，反映了随着针孔准直器直径的增加空间分辨率降低。该拟人头颈部体模为评估用于头颈部区域成像的伽马相机的成像能力提供了有价值的工具。SFOV伽马系统测试体模的标准化将为收集各个医疗中心的数据提供机会。所描述的体模具有成本效益、可重复性、灵活性和解剖学代表性。
A prototype anthropomorphic head and neck phantom has been designed to simulate the adult head and neck anatomy including some internal organs and tissues of interest, such as thyroid gland and sentinel lymph nodes (SLNs). The design of the head and neck phantom includes an inner jig holding the simulated SLNs and thyroid gland. The thyroid gland structure was manufactured using three-dimensional (3D) printing taking into consideration the morphology and shape of a healthy adult thyroid gland. The head and neck phantom was employed to simulate a situation where there are four SLNs distributed at two different vertical levels and at two depths within the neck. Contrast to noise ratio (CNR) calculations were performed for the detected SLNs at an 80 mm distance between both pinhole collimators (0.5 and 1.0 mm diameters) and the surface of the head and neck phantom with a 100 s acquisition time. The recorded CNR values for the simulated SLNs are higher when the hybrid gamma camera (HGC) was fitted with the 1.0 mm diameter pinhole collimator. For instance, the recorded CNR values for the superficially simulated SLN (15 mm depth) containing 0.1 MBq of 99mTc using 0.5 and 1.0 mm diameter pinhole collimators are 6.48 and 16.42, respectively (~87% difference). Gamma and hybrid optical images were acquired using the HGC for the simulated thyroid gland. The count profiles through the middle of the simulated thyroid gland images provided by both pinhole collimators were obtained. The HGC could clearly differentiate the individual peaks of both thyroid lobes in the gamma image produced by the 0.5-mm pinhole collimator. In contrast, the recorded count profile for the acquired image using the 1.0-mm-diameter pinhole collimator showed broader peaks for both lobes, reflecting the degradation of the spatial resolution with increasing the diameter of the pinhole collimator. This anthropomorphic head and neck phantom provides a valuable tool for assessing the imaging ability of gamma cameras used for imaging the head and neck region. The standardisation of test phantoms for SFOV gamma systems will provide an opportunity to collect data across various medical centres. The phantom described is cost effective, reproducible, flexible and anatomically representative.
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DOI：
10.1002/hed.20328
发表时间：
2006-03-01
影响因子：
2.9
作者：
Lin, D;Franc, BL;Singer, MI
通讯作者：
Singer, MI
影响因子：
10.6
作者：
Hellingman, Daan;de Wit-van der Veen, Linda J.;Olmos, Renato A. Valdes
通讯作者：
Olmos, Renato A. Valdes
影响因子：
2.1
作者：
Mah, E;Samei, E;Peck, D J
通讯作者：
Peck, D J
影响因子：
3.8
作者：
Jones, AK;Hintenlang, DE;Bolch, WE
通讯作者：
Bolch, WE
DOI：
10.1259/bjr.20160435
发表时间：
2016-10
期刊：
The British journal of radiology
影响因子：
--
作者：
Alqahtani MS;Lees JE;Bugby SL;Jambi LK;Perkins AC
通讯作者：
Perkins AC