Absence of relationship between oblique muscle size and bielschowsky head tilt phenomenon in clinically diagnosed superior oblique palsy.
Absence of relationship between oblique muscle size and bielschowsky head tilt phenomenon in clinically diagnosed superior oblique palsy.
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DOI：
10.1167/iovs.08-2393
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发表时间：
2009-01
影响因子：
4.4
通讯作者：
Demer JL
中科院分区：
文献类型：
--
作者：
Kono R;Okanobu H;Ohtsuki H;Demer JL
目的：研究临床诊断为上斜肌(SO)麻痹的Bielschowsky头倾斜现象(BHTP)的个体差异是否与最大斜肌大小的差异有关。17名临床诊断为早发性或特发性SO麻痹的受试者和14名正常受试者参加了研究。应用冠状面和矢状面的磁共振成像(MRI)对下斜肌(IO)和SO肌进行定量形态测量。分别在中央注视和偏瘫眼球上斜视下，分别测定SO和IO横截面积的最大值，并比较偏瘫眼上斜视与对侧斜视的差异。正常组平均(±SD)最大SO横截面积为18.1±3.2mm2，瘫痪组为14.2±6.8mm2，对照组为19.2±4.5mm2。自发性SO横截面积明显小于对侧(P=0.004.0 1)和正常(P=0.0 1)。平均IO横截面积正常人为18.3±3.5mm2，患侧为21.3±7.9mm2(P=0.43)，对照组为22.0±6.7mm2(P=0.26)。SO萎缩组和非SO萎缩组大斜度分别为20.1±5.5°和10.3±5.6°(P=0.003)。尽管斜肌横切面与BHTP无关，但临床诊断为严重瘫痪的受试者被分成大小正常和萎缩的两组。因此，BHTP的大小不能解释临床诊断为So麻痹的BHTP的变化，支持BHTP对So功能无特异性这一命题。
To study whether the variation in maximum oblique muscle size accounts for individual variation in the Bielschowsky head tilt phenomenon (BHTP) in clinically diagnosed superior oblique (SO) palsy. Seventeen subjects with clinically diagnosed early-onset or idiopathic SO palsy and 14 normal subjects were enrolled in the study. Magnetic resonance imaging (MRI) in coronal and sagittal planes was used for quantitative morphometry of inferior oblique (IO) and SO muscles. Maximum cross-sectional area of the SO and IO cross section at the mid-inferior rectus crossing were determined in central gaze and compared with paretic eye hypertropia on ipsilesional versus contralesional head tilt. Mean (±SD) maximum SO cross section was 18.1 ± 3.2 mm2 in normal subjects, 14.2 ± 6.8 mm2 ipsilesional to SO palsy, and 19.2 ± 4.5 mm2 contralesional to SO palsy. The ipsilesional SO cross section was significantly smaller than the contralesional (P = 0.004) and normal (P = 0.01) ones. The mean IO cross section was 18.3 ± 3.5 mm2 in normal subjects, 21.3 ± 7.9 mm2 ipsilesional to SO palsy (P = 0.43), and 22.0 ± 6.7 mm2 contralesional to SO palsy (P = 0.26). Hyperdeviation varied with head tilt by 20.1 ± 5.5° in subjects with SO atrophy, and 10.3 ± 5.6° in subjects without SO atrophy (P = 0.003). Although oblique muscle cross sections did not correlate with BHTP, subjects with clinically diagnosed SO palsy segregated into groups exhibiting normal versus atrophic SO size. SO size does not account for the variation in BHTP in clinically diagnosed SO palsy, supporting the proposition that the BHTP is nonspecific for SO function.
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影响因子：
--
作者：
Bielschowsky, A
通讯作者：
Bielschowsky, A
影响因子：
--
作者：
Kushner, BJ
通讯作者：
Kushner, BJ
影响因子：
1.8
作者：
ROBINSON, DA
通讯作者：
ROBINSON, DA
影响因子：
2.5
作者：
Demer, JL;Clark, RA
通讯作者：
Clark, RA
影响因子：
4.2
作者：
Hamasaki, Ichiro;Hasebe, Satoshi;Ohtsuki, Hiroshi
通讯作者：
Ohtsuki, Hiroshi