Validation of case-finding algorithms derived from administrative data for identifying adults living with human immunodeficiency virus infection.

Validation of case-finding algorithms derived from administrative data for identifying adults living with human immunodeficiency virus infection.
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DOI:
10.1371/journal.pone.0021748
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发表时间:
2011
期刊:
影响因子:
3.7
通讯作者:
Glazier RH
Glazier RH
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Antoniou T;Zagorski B;Loutfy MR;Strike C;Glazier RH

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我们试图利用加拿大安大略省的行政卫生数据库验证人类免疫缺陷病毒(HIV)感染的病例发现算法。我们使用医生账单索赔、医院和急诊室的分离以及处方药索赔的组合构建了48个病例查找算法。我们确定了每种算法在不同时间框架内识别HIV感染的测试特征,使用从安大略省多伦多市两家医疗机构随机抽取的2040名患者的图表中提取的数据作为参考标准。除了仅使用单一医生索赔的算法外,所有算法的特异性都超过99%。由三名医生在三年期间的索赔组成的算法的敏感性和特异性分别为96.2% (95% CI 95.2%-97.9%)和99.6% (95% CI 99.1%-99.8%)。将该算法应用于安大略省,确定了2007年4月1日至2009年3月31日期间的12,179名艾滋病毒感染患者。根据行政数据生成的病例查找算法可以准确识别感染艾滋病毒的成年人。一个相对简单的“3年3次索赔”定义可用于组建一个以人口为基础的队列,并促进未来的研究,以审查安大略省感染艾滋病毒的成年人使用保健服务的趋势和结果。
We sought to validate a case-finding algorithm for human immunodeficiency virus (HIV) infection using administrative health databases in Ontario, Canada. We constructed 48 case-finding algorithms using combinations of physician billing claims, hospital and emergency room separations and prescription drug claims. We determined the test characteristics of each algorithm over various time frames for identifying HIV infection, using data abstracted from the charts of 2,040 randomly selected patients receiving care at two medical practices in Toronto, Ontario as the reference standard. With the exception of algorithms using only a single physician claim, the specificity of all algorithms exceeded 99%. An algorithm consisting of three physician claims over a three year period had a sensitivity and specificity of 96.2% (95% CI 95.2%–97.9%) and 99.6% (95% CI 99.1%–99.8%), respectively. Application of the algorithm to the province of Ontario identified 12,179 HIV-infected patients in care for the period spanning April 1, 2007 to March 31, 2009. Case-finding algorithms generated from administrative data can accurately identify adults living with HIV. A relatively simple “3 claims in 3 years” definition can be used for assembling a population-based cohort and facilitating future research examining trends in health service use and outcomes among HIV-infected adults in Ontario.
DOI: 10.1186/cc3811
发表时间: 2005-12-01
期刊: CRITICAL CARE
影响因子: 15.1
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影响因子: 2.8
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DOI: 10.2807/esm.09.10.00481-en
发表时间: 2004-10-01
期刊: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子: --
作者:
Lot, F;Semaille, C;Desenclos, J C
通讯作者: Desenclos, J C