Basilar Artery Plaque and Pontine Infarction Location and Vascular Geometry.
Basilar Artery Plaque and Pontine Infarction Location and Vascular Geometry.
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DOI：
10.5853/jos.2017.00829
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发表时间：
2018-01
影响因子：
8.2
通讯作者：
Chang DI
中科院分区：
文献类型：
--
作者：
Kim BJ;Lee KM;Kim HY;Kim YS;Koh SH;Heo SH;Chang DI
亚临床动脉粥样硬化斑块常见于脑桥梗死（PI）但无基底动脉（BA）狭窄的患者。我们假设BA斑块的位置可能因PI类型和垂直位置以及椎基底动脉几何形状而不同。入组了96例PI但磁共振成像（MRI）和磁共振血管造影显示无BA狭窄的患者。PI按类型（旁正中、深部或外侧）和垂直位置（吻侧、中部或尾部）分类。患者接受高分辨率MRI以评价BA斑块位置（前部、后部或外侧）。测量前后位上BA中角和侧位上BA与优势椎动脉之间的夹角（BA-VA角）。PI为旁正中型（72.9%）、深部型（17.7%）和外侧型（9.4%），垂直位置为吻侧型（32.3%）、中间型（42.7%）和尾侧型（25.0%）。BA斑块的位置因PI类型（P=0.03）和垂直位置（P<0.001）而异，BA斑块在旁正中（37.1%）和尾侧（58.3%）PI的后壁最常见，在外侧（55.5%）和中间（34.1%）PI的侧壁最常见。BA斑块和PI垂直位置不同，BA-VA角和中BA角不同;在后部斑块（P<0.001）和尾部PI（P<0.001）患者中观察到最大BA-VA角。外侧BA斑块（P=0.03）和中间位置PI（P=0.03）观察到最大的中间BA角度。更大的中BA成角可能会增强外侧斑块形成，导致外侧和中部PI，而更大的BA-VA成角可能会增强后部斑块形成，导致旁正中或尾部PI。
Subclinical atherosclerotic plaques are common in patients with pontine infarctions (PIs) but without basilar artery (BA) stenosis. We hypothesized that BA plaque locations may differ by PI type and vertical location as well as vertebrobasilar artery geometry. Ninety-six patients with PI but without BA stenosis on magnetic resonance imaging (MRI) and magnetic resonance angiography were enrolled. PIs were classified by type (paramedian, deep, or lateral) and vertical location (rostral, middle, or caudal). Patients underwent high-resolution MRI to evaluate BA plaque location (anterior, posterior, or lateral). The mid-BA angle on anteroposterior view and angle between the BA and dominant vertebral artery (BA-VA angle) on lateral view were measured. The PIs were paramedian (72.9%), deep (17.7%), and lateral (9.4%) type with a rostral (32.3%), middle (42.7%), and caudal (25.0%) vertical location. The BA plaque locations differed by PI type (P=0.03) and vertical location (P<0.001); BA plaques were most frequent at the posterior wall in paramedian (37.1%) and caudal (58.3%) PIs and at the lateral wall in lateral (55.5%) and middle (34.1%) PIs. The BA-VA and mid-BA angles differed by BA plaque and PI vertical location; the greatest BA-VA angle was observed in patients with posterior plaques (P<0.001) and caudal PIs (P<0.001). Greatest mid-BA angles were observed with lateral BA plaques (P=0.03) and middlelocated PIs (P=0.03). Greater mid-BA angulation may enhance lateral plaque formation, causing lateral and middle PIs, whereas greater BA-VA angulation may enhance posterior plaque formation, causing paramedian or caudal PIs.
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影响因子：
9.9
作者：
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通讯作者：
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