Objective image analysis of the meibomian gland area.
Objective image analysis of the meibomian gland area.
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DOI：
10.1136/bjophthalmol-2012-303014
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发表时间：
2014-06
期刊：
影响因子：
--
通讯作者：
Amano S
中科院分区：
文献类型：
--
作者：
Arita R;Suehiro J;Haraguchi T;Shirakawa R;Tokoro H;Amano S
使用新开发的非侵入性睑板腺成像软件客观地评估睑板腺区域。 42 名无睑板腺丧失的患者的 80 个眼睑（meiboscore=0），57 名睑板腺总面积丧失少于三分之一的患者的 105 个眼睑（meiboscore=1），11 名睑板腺面积丧失三分之一至三分之二的患者的 13 个眼睑（meiboscore=2）以及 14 名丧失三分之二的患者的 20 个眼睑的 研究了睑板腺区域（meiboscore=3）。盖子边界是自动确定的。该软件评估亮度分布，并通过增强对比度和减少图像噪声，自动区分睑板腺区域。该软件计算了所有受试者的睑板腺总面积相对于总分析面积的比率。还评估了软件的可重复性。睑板腺面积与上/下眼睑总分析面积的平均比率，睑板评分为0的受试者为51.9±5.7%/54.7±5.4%，睑板评分为1的受试者为47.7±6.0%/51.5±5.4%，睑板评分为1的受试者为32.0±4.4%/37.2±3.5%。 meibo分数为2并且 睑板腺评分为 3 的受试者为 16.7±6.4%/19.5±5.8%。使用开发的软件客观评估睑板腺面积。该系统可用于客观评估睑板腺功能障碍的治疗效果。
To evaluate objectively the meibomian gland area using newly developed software for non-invasive meibography. Eighty eyelids of 42 patients without meibomian gland loss (meiboscore=0), 105 eyelids of 57 patients with loss of less than one-third total meibomian gland area (meiboscore=1), 13 eyelids of 11 patients with between one-third and two-thirds loss of meibomian gland area (meiboscore=2) and 20 eyelids of 14 patients with two-thirds loss of meibomian gland area (meiboscore=3) were studied. Lid borders were automatically determined. The software evaluated the distribution of the luminance and, by enhancing the contrast and reducing image noise, the meibomian gland area was automatically discriminated. The software calculated the ratio of the total meibomian gland area relative to the total analysis area in all subjects. Repeatability of the software was also evaluated. The mean ratio of the meibomian gland area to the total analysis area in the upper/lower eyelids was 51.9±5.7%/54.7±5.4% in subjects with a meiboscore of 0, 47.7±6.0%/51.5±5.4% in those with a meiboscore of 1, 32.0±4.4%/37.2±3.5% in those with a meiboscore of 2 and 16.7±6.4%/19.5±5.8% in subjects with a meiboscore of 3. The meibomian gland area was objectively evaluated using the developed software. This system could be useful for objectively evaluating the effect of treatment on meibomian gland dysfunction.
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影响因子：
2.8
作者：
Pflugfelder, SC;Tseng, SCG;Reis, BL
通讯作者：
Reis, BL
影响因子：
6.4
作者：
Ban, Yumiko;Shimazaki-Den, Seika;Shimazaki, Jun
通讯作者：
Shimazaki, Jun
影响因子：
2.4
作者：
Arita, Reiko;Itoh, Kouzo;Amano, Shiro
通讯作者：
Amano, Shiro
影响因子：
1.4
作者：
Ong, BL
通讯作者：
Ong, BL
影响因子：
2.8
作者：
Arita, Reiko;Itoh, Kouzo;Amano, Shiro
通讯作者：
Amano, Shiro