Big roles of small kinases: the complex functions of receptor-like cytoplasmic kinases in plant immunity and development.

Big roles of small kinases: the complex functions of receptor-like cytoplasmic kinases in plant immunity and development.
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DOI:
10.1111/jipb.12071
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发表时间:
2013-12
影响因子:
11.4
通讯作者:
He P
He P
中科院分区:
生物学1区
文献类型:
--
作者:
Lin W;Ma X;Shan L;He P

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植物中存在大量的受体样胞质激酶(receptor-like cytoplasmic kinases,RLCK),它们与受体样激酶(receptor-like kinases,RLKs)在功能和物理上相互作用,共同调节植物的生长发育和免疫应答。没有任何明显的胞外结构域,RLCK通常通过RLK复合物介导的转磷酸化事件传递细胞内信号。最近的进展表明,在调节各种细胞和生理反应中,各种RLCK与RLKs一起发挥重要作用。本文综述了RLCKs在介导植物免疫应答和生长调节中的复杂作用,并讨论了RLCKs在不同信号转导途径中的特异性和重叠功能。
Plants have evolved a large number of receptor-like cytoplasmic kinases (RLCKs) that often functionally and physically associate with receptor-like kinases (RLKs) to modulate plant growth, development and immune responses. Without any apparent extracellular domain, RLCKs relay intracellular signaling often via RLK complex-mediated transphosphorylation events. Recent advances have suggested essential roles of diverse RLCKs in concert with RLKs in regulating various cellular and physiological responses. We summarize here the complex roles of RLCKs in mediating plant immune responses and growth regulation, and discuss specific and overlapping functions of RLCKs in transducing diverse signaling pathways.
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