The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.
The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.
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DOI:
10.1016/j.cmet.2012.03.004
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发表时间:
2012-05-02
期刊:
影响因子:
29
通讯作者:
Walther TC
中科院分区:
文献类型:
--
作者:
Farese RV Jr;Zechner R;Newgard CB;Walther TC
Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.
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影响因子:
4.4
作者:
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通讯作者:
Biddinger SB
影响因子:
16
作者:
Shimomura, I;Matsuda, M;Goldstein, JL
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DOI:
10.1126/science.1204265
发表时间:
2011-06-24
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Cohen JC;Horton JD;Hobbs HH
通讯作者:
Hobbs HH