The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.

The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.
复制标题

DOI:
10.1016/j.cmet.2012.03.004
复制
发表时间:
2012-05-02
期刊:
影响因子:
29
通讯作者:
Walther TC
Walther TC
中科院分区:
生物学1区
文献类型:
--
作者:
Farese RV Jr;Zechner R;Newgard CB;Walther TC

文献摘要

参考文献

被引文献

相似文献

脂肪在肝脏中的过度沉积(肝性脂肪变性)经常伴随着肝胰岛素抵抗。这种相关性是否是由于条件之间的因果关系引起的一直是相当多争论的主题,文献中充满了相互矛盾的数据和理论。在这里,我们通过定义问题及其挑战,分析可能的因果关系,并得出一些结论,提供了一个视角。
Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.
DOI: 10.1097/mol.0b013e32832b2024
发表时间: 2009-06
影响因子: 4.4
作者:
Haas JT;Biddinger SB
通讯作者: Biddinger SB
DOI: 10.1016/s1097-2765(00)00009-5
发表时间: 2000-07-01
期刊: MOLECULAR CELL
影响因子: 16
作者:
Shimomura, I;Matsuda, M;Goldstein, JL
通讯作者: Goldstein, JL
DOI: 10.2337/db06-s002
发表时间: 2006-12-01
期刊: DIABETES
影响因子: 7.7
作者:
Morino, Katsutaro;Petersen, Kitt Falk;Shulman, Gerald I.
通讯作者: Shulman, Gerald I.
DOI: 10.1194/jlr.m010256
发表时间: 2010-11-01
影响因子: 6.5
作者:
Brown, J. Mark;Betters, Jenna L.;Yu, Liqing
通讯作者: Yu, Liqing
人类脂肪肝病:旧问题和新见解。
DOI: 10.1126/science.1204265
发表时间: 2011-06-24
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Cohen JC;Horton JD;Hobbs HH
通讯作者: Hobbs HH