Human Erythrocyte Antigens

Human Erythrocyte Antigens
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人类红细胞抗原

DOI:
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发表时间:
1987
期刊:
影响因子:
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通讯作者:
B. Haynes
B. Haynes
中科院分区:
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文献类型:
--
作者:
M. Telen;R. Scearce;B. Haynes

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抽象。人红细胞膜蛋白表达抗原,其用作红细胞分化的标志物以及人血型同种抗体的靶标。我们已经产生并表征了一个新的面板的五个单克隆抗体红细胞膜蛋白。三种单克隆抗体(E3、E4、E5)对红细胞血型糖蛋白具有特异性。一种抗体(E3)鉴定了质膜近端的唾液酸糖蛋白α和β同源区,第二种抗体(E4)对唾液酸糖蛋白α具有特异性,而第三种抗体(E5)是唾液酸糖蛋白β特异性抗体。还产生了针对条带3的65,000-道尔顿胰凝乳蛋白酶切割产物的两种抗体(E6和TE 10)。这些抗体构成了一组新的探针,用于研究正常红细胞分化、红白血病以及正常和异常血型抗原的表达。
Abstract. Human erythrocyte membrane proteins express antigens which serve as markers for erythroid differentiation as well as targets for human blood group alloantibodies. We have produced and characterized a new panel of five monoclonal antibodies to erythrocyte membrane proteins. Three monoclonal antibodies (E3, E4, E5) were specific for erythrocyte glycophorins. One antibody (E3) identified the sialoglycoprotein α and β homologous regions proximal to the plasma membrane, a second antibody (E4) was specific for sialoglycoprotein α, while a third (E5) was a sialogylcoprotein‐β‐specific antibody. Two antibodies (E6 and TE10) to the 65,000‐dalton chymotrypsin cleavage product of band 3 were also produced. These antibodies constitute a new panel of probes for investigation of normal erythroid differentiation, erythroleukemia, and the expression of normal and anomalous blood group antigens.
DOI: 10.1126/science.6177045
发表时间: 1982-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
MARTIN, P;PAPAYANNOPOULOU, T
通讯作者: PAPAYANNOPOULOU, T
五种单克隆抗体与人红细胞糖蛋白 A 反应的不同特异性。
DOI: --
发表时间: 1983
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Ochiai,Y;Furthmayr,H;Marcus,DM
通讯作者: Marcus,DM
DOI: --
发表时间: 1983
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Haynes,BF;Harden,EA;Telen,MJ;Hemler,ME;Strominger,JL;Palker,TJ;Scearce,RM;Eisenbarth,GS
通讯作者: Eisenbarth,GS
皮肤 T 细胞淋巴瘤中皮肤浸润 T 细胞的表型特征:与良性皮肤 T 细胞浸润的比较。
DOI: --
发表时间: 1982
期刊: Blood
影响因子: 20.3
作者:
Haynes,BF;Hensley,LL;Jegasothy,BV
通讯作者: Jegasothy,BV
DOI: --
发表时间: 1984
期刊: Blood
影响因子: 20.3
作者:
Telen,MJ;Palker,TJ;Haynes,BF
通讯作者: Haynes,BF