Impact of the gut microbiome on mucosal inflammation.
Impact of the gut microbiome on mucosal inflammation.
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DOI:
10.1016/j.it.2013.07.001
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发表时间:
2013-09
影响因子:
16.8
通讯作者:
Strober W
中科院分区:
文献类型:
--
作者:
Strober W
In the last 10 years it has become increasingly apparent that the gut microbiome has profound effects on the immune system to which it is juxtaposed, the mucosal immune system. Here I explore recent studies in which the effects of the microbiota expand or facilitate anti-inflammatory or regulatory immunologic machinery or which favor development of pro-inflammatory immunologic machinery in this system. I then focus on how these opposing processes play out in inflammatory bowel disease, a disease in which normal immune homeostasis is disturbed and inflammation takes hold.
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DOI:
10.1126/science.1198469
发表时间:
2011-01-21
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Atarashi K;Tanoue T;Shima T;Imaoka A;Kuwahara T;Momose Y;Cheng G;Yamasaki S;Saito T;Ohba Y;Taniguchi T;Takeda K;Hori S;Ivanov II;Umesaki Y;Itoh K;Honda K
通讯作者:
Honda K
影响因子:
5
作者:
Bringer, Marie-Agnes;Billard, Elisabeth;Darfeuille-Michaud, Arlette
通讯作者:
Darfeuille-Michaud, Arlette
影响因子:
3.4
作者:
Lapaquette, Pierre;Bringer, Marie-Agnes;Darfeuille-Michaud, Arlette
通讯作者:
Darfeuille-Michaud, Arlette
影响因子:
4.9
作者:
Frank, Daniel N.;Robertson, Charles E.;Hamm, Christina M.;Kpadeh, Zegbeh;Zhang, Tianyi;Chen, Hongyan;Zhu, Wei;Sartor, R. Balfour;Boedeker, Edgar C.;Harpaz, Noam;Pace, Norman R.;Li, Ellen
通讯作者:
Li, Ellen
影响因子:
29.7
作者:
Kaser A;Zeissig S;Blumberg RS
通讯作者:
Blumberg RS