Characteristics and comparison between diabetes mellitus and non-diabetes mellitus among chronic kidney disease patients: A cross-sectional study of the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE).
Characteristics and comparison between diabetes mellitus and non-diabetes mellitus among chronic kidney disease patients: A cross-sectional study of the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE).
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DOI：
10.18632/oncotarget.22368
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发表时间：
2017-12-05
期刊：
影响因子：
--
通讯作者：
Liu ZS
中科院分区：
文献类型：
--
作者：
Zhang JJ;Yang L;Huang JW;Liu YJ;Wang JW;Zhang LX;Zhao MH;Liu ZS
尽管全球慢性肾脏病（CKD）和糖尿病（DM）的患病率正在增加，但缺乏中国慢性肾脏病（CKD）合并糖尿病（DM）患者的信息。2011年11月至2016年4月，中国慢性肾脏病队列研究（C-STRIDE）共入组了3499例来自中国各地的透析前CKD患者。在这项横断面研究中，我们将C-STRIDE患者分为CKD伴DM组和CKD不伴DM组，并比较了他们的临床、人口统计学和实验室数据。CKD合并DM患者年龄较大，男女比例较高，并发症多于CKD不伴DM患者。年龄、吸烟和24小时尿蛋白水平与CKD和DM的共同发生相关。两组中均少于50%的患者服用了降血脂、心血管、脑血管或抗贫血药物。此外，只有18.38%的CKD合并糖尿病患者接受了肾活检，其中35.4%的患者被证实患有糖尿病肾病。我们的研究结果表明，几种类型的药物和肾活检应更频繁地用于治疗中国CKD患者的DM。
Although the prevalence of chronic kidney disease (CKD) and diabetes mellitus (DM) is increasing globally, information on Chinese CKD patients with DM is lacking. A total of 3499 pre-dialysis CKD patients from across China were enrolled in the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE) between November 2011 and April 2016. We divided the C-STRIDE patients into CKD with DM and CKD without DM groups and compared their clinical, demographic, and laboratory data in this cross-sectional study. CKD patients with DM were older, had a higher male-to-female ratio, and had more complications than CKD patients without DM. Age, smoking, and 24-h urinary protein levels were associated with co-occurrence of CKD and DM. Less than 50% of patients in either group took antilipemic, cardiovascular, cerebrovascular, or anti-anemic drugs. In addition, only 18.38% of CKD patients with DM had undergone a renal biopsy, and diabetic nephropathy was confirmed in 35.4% of them. Our findings suggest that several types of medication and renal biopsies should be used more frequently in the treatment of Chinese CKD patients with DM.
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影响因子：
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Chen XM
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影响因子：
2.3
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影响因子：
2.3
作者：
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