Precursor lesions for sporadic pancreatic cancer: PanIN, IPMN, and MCN.

Precursor lesions for sporadic pancreatic cancer: PanIN, IPMN, and MCN.
复制标题

DOI:
10.1155/2014/474905
复制
发表时间:
2014
影响因子:
--
通讯作者:
Grützmann R
Grützmann R
中科院分区:
生物学3区
文献类型:
--
作者:
Distler M;Aust D;Weitz J;Pilarsky C;Grützmann R

文献摘要

参考文献

被引文献

相似文献

胰腺癌仍然是一种令人沮丧的疾病。死亡率高的主要原因是缺乏高度敏感和特异的诊断工具,大多数患者被诊断为晚期且无法治愈。在过去的十年中,关于胰腺癌先兆病变的认识显著增加,目前我们知道主要有三种病变(Panin,和IPMN,MCN)与胰腺癌的发生有关。这些病变的早期检测仍然具有挑战性,但为在患者可能患上侵袭性胰腺癌之前治愈他们提供了机会。本文重点介绍了Panin、IPMN和MCN的病变,并对目前的知识水平和临床措施进行了综述。
Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures.
DOI: 10.1097/01.mp.0000028647.98725.8b
发表时间: 2002-10-01
期刊: MODERN PATHOLOGY
影响因子: 7.5
作者:
Adsay, NV;Merati, K;Klimstra, DS
通讯作者: Klimstra, DS
DOI: 10.1007/s00428-005-0039-7
发表时间: 2005-11-01
期刊: VIRCHOWS ARCHIV
影响因子: 3.5
作者:
Furukawa, T;Klöppel, G;Yonezawa, S
通讯作者: Yonezawa, S
DOI: 10.1038/srep00161
发表时间: 2011
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Furukawa, Toru;Kuboki, Yuko;Tanji, Etsuko;Yoshida, Shoko;Hatori, Takashi;Yamamoto, Masakazu;Shibata, Noriyuki;Shimizu, Kyoko;Kamatani, Naoyuki;Shiratori, Keiko
通讯作者: Shiratori, Keiko
DOI: 10.1007/s00104-009-1861-2
发表时间: 2010-08-01
期刊: CHIRURG
影响因子: --
作者:
Gruetzmann, R.;Saeger, H. -D.
通讯作者: Saeger, H. -D.