Crosstalk Between Adipose Tissue and the Heart: An Update.
Crosstalk Between Adipose Tissue and the Heart: An Update.
复制标题
DOI:
10.2478/jtim-2022-0039
复制
发表时间:
2022-09
影响因子:
4.9
通讯作者:
Scherer, Philipp E.
中科院分区:
文献类型:
--
作者:
Li, Chao;Sun, Xue-Nan;Zhao, Shangang;Scherer, Philipp E.
It is important to understand how different human organs coordinate and interact with each other. Since obesity and cardiac disease frequently coincide, the crosstalk between adipose tissues and heart has drawn attention. We appreciate that specific peptides/proteins, lipids, nucleic acids, and even organelles shuttle between the adipose tissues and heart. These bioactive components can profoundly affect the metabolism of cells in distal organs, including heart. Importantly, this process can be dysregulated under pathophysiological conditions. This also opens the door to efforts targeting these mediators as potential therapeutic strategies to treat patients who manifest diabetes and cardiovascular disease. Here, we summarize the recent progress toward a better understanding of how the adipose tissues and heart interact with each other.
登录
查看更多内容
影响因子:
64.5
作者:
Cao H;Gerhold K;Mayers JR;Wiest MM;Watkins SM;Hotamisligil GS
通讯作者:
Hotamisligil GS
影响因子:
29
作者:
Crewe C;Funcke JB;Li S;Joffin N;Gliniak CM;Ghaben AL;An YA;Sadek HA;Gordillo R;Akgul Y;Chen S;Samovski D;Fischer-Posovszky P;Kusminski CM;Klein S;Scherer PE
通讯作者:
Scherer PE
影响因子:
3.7
作者:
Corradi, D;Maestri, R;Bordi, C
通讯作者:
Bordi, C
影响因子:
4.8
作者:
Hasty, AH;Shimano, H;Yamada, N
通讯作者:
Yamada, N
影响因子:
17.1
作者:
Cimen, Ismail;Kocaturk, Begum;Erbay, Ebru
通讯作者:
Erbay, Ebru