Tipping the balance by manipulating post-translational modifications.
Tipping the balance by manipulating post-translational modifications.
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DOI:
10.1016/j.mib.2009.12.004
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发表时间:
2010-02
影响因子:
5.4
通讯作者:
Orth, Kim
中科院分区:
文献类型:
--
作者:
Broberg, Christopher A.;Orth, Kim
Bacteria use a variety of mechanisms during infection to ensure their survival including the delivery of virulence factors via a type III secretion system into the infected cell. The factors exhibit diverse activities that in many cases mimic eukaryotic mechanisms used by the host to defend against infection. Herein we describe a class of effectors that use posttranslational modifications, some reversible and others irreversible, to manipulate host signaling systems to subvert the host response.
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影响因子:
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