Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos
Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos
复制标题
组织果蝇胚胎前后体模式的不同策略
作者：
G. Struhl
相反的前部和后部形态发生系统规定了果蝇的体节模式。前形态原bicoid通过其沿身体沿着的浓度变化触发不同的结果，对头部和胸部图案施加直接的指导性影响。与此相反，后部形态发生原nanos通过消除胚胎后半部分普遍存在的抑制蛋白hunchback蛋白，简单地定义了腹部模式发生的位置。在这个驼背的自由域的模式腹节必须指定由其他形态发生，可能由较短的范围梯度的合子间隙基因Kruppel，knirps和无尾的产品。
Opposing anterior and posterior morphogen systems specify the segmented body pattern of Drosophila. The anterior morphogen, bicoid, exerts a direct instructive influence on head and thoracic pattern by triggering different outcomes according to changes in its concentration along the body. In contrast the posterior morphogen, nanos, simply defines where abdominal patterning can occur by eliminating an otherwise ubiquitous repressor, hunchback protein, from the posterior half of the embryo. Within this hunchback-free domain the pattern of abdominal segments must be specified by other morphogens, possibly by shorter range gradients of the products of zygotic gap genes Kruppel, knirps and tailless.
无尾合子突变体影响果蝇胚胎的前外胚层区域和后外胚层区域。
影响因子：
2.7
作者：
Strecker,TR;Kongsuwan,K;Lengyel,JA;Merriam,JR
通讯作者：
Merriam,JR