Interaction of integration host factor from Escherichia coli with the integration region of the Haemophilus influenzae bacteriophage HP1

Interaction of integration host factor from Escherichia coli with the integration region of the Haemophilus influenzae bacteriophage HP1
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大肠杆菌整合宿主因子与流感嗜血杆菌噬菌体 HP1 整合区域的相互作用

DOI:
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发表时间:
1990
影响因子:
3.2
通讯作者:
J. J. Scocca
J. J. Scocca
中科院分区:
生物学3区
文献类型:
--
作者:
E. Hwang;J. J. Scocca

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The specific DNA-binding protein integration host factor (IHF) of Escherichia coli stimulates the site-specific recombination reaction between the attP site of bacteriophage HP1 and the attB site of its host, Haemophilus influenzae, in vitro and also appears to regulate the expression of HP1 integrase. IHF interacts specifically with DNA segments containing the att sites and the integrase regulatory region, as judged by IHF-dependent retardation of relevant DNA fragments during gel electrophoresis. The locations of the protein-binding sites were identified by DNase I protection experiments. Three sites in the HP1 attP region bound IHF, two binding sites were present in the vicinity of the attB region, and one region containing three partially overlapping sites was present in the HP1 integrase regulatory segment. The binding sites defined in these experiments all contained sequences which matched the consensus IHF binding sequences first identified in the lambda attP region. An activity which stimulated the HP1 site-specific integration reaction was found in extracts of H. influenzae, suggesting that an IHF-like protein is present in this organism.
羔羊噬菌体位点特异性重组基因之间的结构和调控差异。
DOI: 10.1016/0022-2836(86)90491-2
发表时间: 1986
影响因子: 5.6
作者:
Leong,JM;Nunes-Düby,SE;Oser,AB;Lesser,CF;Youderian,P;Susskind,MM;Landy,A
通讯作者: Landy,A
整合宿主因子 (IHF) 抑制大肠杆菌中的衣藻叶绿体启动子。
DOI: 10.1093/nar/16.8.3313
发表时间: 1988
影响因子: 14.9
作者:
Thompson,RJ;Mosig,G
通讯作者: Mosig,G
噬菌体 lambda att 位点的结构和功能:大小、int 结合位点和交叉点的位置。
DOI: 10.1101/sqb.1981.045.01.057
发表时间: 1981
期刊: Cold Spring Harbor symposia on quantitative biology
影响因子: --
作者:
Mizuuchi,K;Weisberg,R;Enquist,L;Mizuuchi,M;Buraczynska,M;Foeller,C;Hsu,PL;Ross,W;Landy,A
通讯作者: Landy,A