Selective cancer cell killing by alpha-tocopheryl succinate.
Selective cancer cell killing by alpha-tocopheryl succinate.
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DOI:
10.1054/bjoc.2000.1559
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发表时间:
2001-01-05
影响因子:
8.8
通讯作者:
Weber C
中科院分区:
文献类型:
--
作者:
Neuzil J;Weber T;Gellert N;Weber C
We report that α-tocopheryl succinate, a vitamin E analogue with pro-apoptotic properties, selectively kills cells with a malignant or transformed phenotype, i.e. multiple haematopoietic and carcinoma cell lines, while being non-toxic to normal, i.e. primary and non-transformed cells. These findings strongly suggest a potential of this micronutrient in the therapy and/or prevention of cancer without significant side-effects. © 2001 Cancer Research Campaign http://www.bjcancer.com
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影响因子:
3.5
作者:
Neuzil, J;Svensson, I;Brunk, UT
通讯作者:
Brunk, UT
影响因子:
8
作者:
Qian, M;Kralova, J;Kline, K
通讯作者:
Kline, K
影响因子:
15.9
作者:
WAYS, DK;KUKOLY, CA;PARKER, PJ
通讯作者:
PARKER, PJ
影响因子:
7.1
作者:
BENDICH, A;MACHLIN, LJ
通讯作者:
MACHLIN, LJ
影响因子:
2.9
作者:
Israel, K;Yu, WP;Kline, K
通讯作者:
Kline, K