Endoscopic imaging in Barrett’s esophagus

Endoscopic imaging in Barrett’s esophagus
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巴雷特食管的内窥镜成像

DOI:
10.1586/17474124.2015.983080
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发表时间:
2015
影响因子:
3.9
通讯作者:
S. Yeap
S. Yeap
中科院分区:
医学3区
文献类型:
--
作者:
Rajvinder Singh;S. Yeap

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巴雷特食管是唯一已知的使患者易于发展为食管腺癌的前体。目前推荐的监测方法是对任何异常进行靶向活检,然后使用标准白色光内镜每2 cm进行随机四象限活检。遵守这一点和抽样误差是两个最大的问题。几种新的成像技术已被开发出来,以帮助诊断早期肿瘤在巴雷特食管。有新的数据表明,这些新的模式可以提高检测异型增生的产量。本文将讨论一些目前可用的技术和技术,包括色素内镜,窄带成像,自体荧光成像,光学相干断层扫描,共聚焦显微内镜和胞内镜。根据目前的证据,这些成像模式似乎是有前途的白色光内窥镜检查的辅助工具。然而,其中一些仍然是实验性的,由于费用,缺乏专业知识,普遍性以及结果的可重复性。
Barrett’s esophagus is the only known precursor that predisposes patients to the development of esophageal adenocarcinoma. The current recommended surveillance method is targeted biopsies of any abnormalities followed by random four-quadrant biopsies every 2 cm using standard white light endoscopy. Compliance with this and sampling error are two of the biggest problems. Several novel imaging technologies have been developed to aid the diagnosis of early neoplasia in Barrett’s esophagus. There are emerging data that some of these new modalities can increase the yield of detecting dysplasia. This review will discuss some of the present available techniques and technologies including chromoendoscopy, narrow-band imaging, autofluorescence imaging, optical coherence tomography, confocal endomicroscopy and endocytoscopy. Based on the current evidence, these imaging modalities appear to be promising as adjunctive tools to white light endoscopy. A few of them, nevertheless, remain experimental due to expense, lack of expertise, generalizability as well as reproducibility of results.
使用内窥镜三维光学相干断层扫描观察到的结构标记与巴雷特食管射频消融治疗反应相关(带视频)。
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期刊: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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