Enterotypes in the landscape of gut microbial community composition.
Enterotypes in the landscape of gut microbial community composition.
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DOI:
10.1038/s41564-017-0072-8
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发表时间:
2018-01
影响因子:
28.3
通讯作者:
Bork P
中科院分区:
文献类型:
--
作者:
Costea PI;Hildebrand F;Arumugam M;Bäckhed F;Blaser MJ;Bushman FD;de Vos WM;Ehrlich SD;Fraser CM;Hattori M;Huttenhower C;Jeffery IB;Knights D;Lewis JD;Ley RE;Ochman H;O'Toole PW;Quince C;Relman DA;Shanahan F;Sunagawa S;Wang J;Weinstock GM;Wu GD;Zeller G;Zhao L;Raes J;Knight R;Bork P
Population stratification is a useful approach towards a better understanding of complex biological problems in human health and well-being. The proposal that such stratification applies to the human gut microbiome, in the form of distinct community composition types, termed “enterotypes”, was met with both excitement and controversy. In view of accumulated data and re-analyses since the original work, we revisit the enterotype concept, discuss different methods of dividing up the landscape of possible microbiome configurations, and put these concepts into a functional, ecological and medical context. As enterotypes are of use in describing the gut microbial community landscape and may become relevant in clinical practice, we aim to reconcile differing views and encourage a balanced application of the concept.
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影响因子:
64.8
作者:
通讯作者:
--
影响因子:
64.8
作者:
Arumugam, Manimozhiyan;Raes, Jeroen;Pelletier, Eric;Le Paslier, Denis;Yamada, Takuji;Mende, Daniel R.;Fernandes, Gabriel R.;Tap, Julien;Bruls, Thomas;Batto, Jean-Michel;Bertalan, Marcelo;Borruel, Natalia;Casellas, Francesc;Fernandez, Leyden;Gautier, Laurent;Hansen, Torben;Hattori, Masahira;Hayashi, Tetsuya;Kleerebezem, Michiel;Kurokawa, Ken;Leclerc, Marion;Levenez, Florence;Manichanh, Chaysavanh;Nielsen, H. Bjorn;Nielsen, Trine;Pons, Nicolas;Poulain, Julie;Qin, Junjie;Sicheritz-Ponten, Thomas;Tims, Sebastian;Torrents, David;Ugarte, Edgardo;Zoetendal, Erwin G.;Wang, Jun;Guarner, Francisco;Pedersen, Oluf;de Vos, Willem M.;Brunak, Soren;Dore, Joel;Weissenbach, Jean;Ehrlich, S. Dusko;Bork, Peer
通讯作者:
Bork, Peer
影响因子:
15.5
作者:
Gorvitovskaia A;Holmes SP;Huse SM
通讯作者:
Huse SM
影响因子:
46.9
作者:
Costea, Paul I.;Zeller, Georg;Bork, Peer
通讯作者:
Bork, Peer
影响因子:
12.3
作者:
Hildebrand F;Nguyen TL;Brinkman B;Yunta RG;Cauwe B;Vandenabeele P;Liston A;Raes J
通讯作者:
Raes J