Deep learning analysis of single-cell data in empowering clinical implementation.
Deep learning analysis of single-cell data in empowering clinical implementation.
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单细胞数据的深度学习分析,为临床实施提供支持。
DOI:
10.1002/ctm2.950
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发表时间:
2022-07
影响因子:
10.6
通讯作者:
中科院分区:
文献类型:
--
作者:
Recent advances in single-cell sequencing technologies enable the characterization of cellular heterogeneity and biological processes in complex diseases. This provides unprecedented opportunities to understand disease pathology at a level that allows mechanistic classification and development of precision therapeutic strategies. Extensive research has been performed in clinical studies at the single-cell level. 1 In addition, emerging deep learning (DL) technologies hold great potential in modeling large-volume and highly heterogeneous single-cell data by using sophisticated architectures, such as artificial neural networks, 2 for translational and clinical purpose. 3 In this commentary, we focus on the DL analysis of singlecell data in empowering the clinical implementation of personalized medicine.
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影响因子:
5.5
作者:
通讯作者:
--
影响因子:
13.8
作者:
Wu Z;Lawrence PJ;Ma A;Zhu J;Xu D;Ma Q
通讯作者:
Ma Q
影响因子:
12.3
作者:
Tran KA;Kondrashova O;Bradley A;Williams ED;Pearson JV;Waddell N
通讯作者:
Waddell N
影响因子:
3.5
作者:
Xia J;Wang L;Zhang G;Zuo C;Chen L
通讯作者:
Chen L
影响因子:
64.8
作者:
Rajewsky N;Almouzni G;Gorski SA;Aerts S;Amit I;Bertero MG;Bock C;Bredenoord AL;Cavalli G;Chiocca S;Clevers H;De Strooper B;Eggert A;Ellenberg J;Fernández XM;Figlerowicz M;Gasser SM;Hubner N;Kjems J;Knoblich JA;Krabbe G;Lichter P;Linnarsson S;Marine JC;Marioni JC;Marti-Renom MA;Netea MG;Nickel D;Nollmann M;Novak HR;Parkinson H;Piccolo S;Pinheiro I;Pombo A;Popp C;Reik W;Roman-Roman S;Rosenstiel P;Schultze JL;Stegle O;Tanay A;Testa G;Thanos D;Theis FJ;Torres-Padilla ME;Valencia A;Vallot C;van Oudenaarden A;Vidal M;Voet T;LifeTime Community Working Groups
通讯作者:
LifeTime Community Working Groups