ADHD Remote Technology study of cardiometabolic risk factors and medication adherence (ART-CARMA): a multi-centre prospective cohort study protocol.
ADHD Remote Technology study of cardiometabolic risk factors and medication adherence (ART-CARMA): a multi-centre prospective cohort study protocol.
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心脏代谢风险因素和药物依从性（ART-CARMA）的ADHD远程技术研究：多中心的前瞻性队列研究方案。
DOI：
10.1186/s12888-022-04429-6
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发表时间：
2022-12-20
期刊：
影响因子：
4.4
通讯作者：
中科院分区：
文献类型：
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作者：
新出现的证据表明成人注意缺陷多动障碍（ADHD）和心脏代谢疾病之间存在大量的共病，但我们对ADHD成人的共病和如何管理心脏代谢疾病的理解有限。心脏代谢风险因素和药物依从性的ADHD远程技术研究（ART-CARMA）项目使用远程测量技术从日常生活中获得真实世界的数据，以评估ADHD药物治疗和身体活动单独或联合可能影响ADHD成人心脏代谢风险的程度。我们的第二个主要目标是获得有价值的现实世界的数据，坚持药物治疗及其预测因子和相关性在日常生活中从成人多动症。ART-CARMA是欧盟资助的合作“TIMESPAN”（成人ADHD患者慢性心脏代谢疾病和治疗中断的管理）中的一项多中心前瞻性队列研究，将从成人ADHD等待名单中招募300名成人。从治疗前开始，将在12个月的时间内对参与者进行远程监测。被动监测，参与者佩戴腕戴式设备（EmbracePlus）并在智能手机上下载基于雷达的被动应用程序和Empatica Care应用程序，提供关于各种变量的持续数据收集，例如体力活动、睡眠、脉搏率（PR）和脉搏率变异性（PRV）、收缩峰值、皮肤电活动（EDA）、血氧饱和度（SpO 2）、外周温度、智能手机使用情况，包括社交连接和环境（例如环境噪声、光照水平、相对位置）。通过组合这些测量变量的数据，可以捕获身体活动，睡眠，自主觉醒和心血管健康指标等过程。主动远程监测涉及参与者使用智能手机应用程序完成任务（例如完成临床问卷或语音任务），测量血压和体重，或使用PC/笔记本电脑（认知任务）。ART系统建立在基于雷达的移动健康平台上。长期目标是使用这些数据来改善ADHD成人心脏代谢疾病的管理，并改善ADHD药物治疗依从性和治疗的个性化。
Emerging evidence points at substantial comorbidity between adult attention deficit hyperactivity disorder (ADHD) and cardiometabolic diseases, but our understanding of the comorbidity and how to manage cardiometabolic disease in adults with ADHD is limited. The ADHD Remote Technology study of cardiometabolic risk factors and medication adherence (ART-CARMA) project uses remote measurement technology to obtain real-world data from daily life to assess the extent to which ADHD medication treatment and physical activity, individually and jointly, may influence cardiometabolic risks in adults with ADHD. Our second main aim is to obtain valuable real-world data on adherence to pharmacological treatment and its predictors and correlates during daily life from adults with ADHD. ART-CARMA is a multi-site prospective cohort study within the EU-funded collaboration ‘TIMESPAN’ (Management of chronic cardiometabolic disease and treatment discontinuity in adult ADHD patients) that will recruit 300 adults from adult ADHD waiting lists. The participants will be monitored remotely over a period of 12 months that starts from pre-treatment initiation. Passive monitoring, which involves the participants wearing a wrist-worn device (EmbracePlus) and downloading the RADAR-base Passive App and the Empatica Care App on their smartphone, provides ongoing data collection on a wide range of variables, such as physical activity, sleep, pulse rate (PR) and pulse rate variability (PRV), systolic peaks, electrodermal activity (EDA), oxygen saturation (SpO2), peripheral temperature, smartphone usage including social connectivity, and the environment (e.g. ambient noise, light levels, relative location). By combining data across these variables measured, processes such as physical activity, sleep, autonomic arousal, and indicators of cardiovascular health can be captured. Active remote monitoring involves the participant completing tasks using a smartphone app (such as completing clinical questionnaires or speech tasks), measuring their blood pressure and weight, or using a PC/laptop (cognitive tasks). The ART system is built on the RADAR-base mobile-health platform. The long-term goal is to use these data to improve the management of cardiometabolic disease in adults with ADHD, and to improve ADHD medication treatment adherence and the personalisation of treatment.
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DOI：
10.1186/cc2955
发表时间：
2004-10
期刊：
Critical care (London, England)
影响因子：
--
作者：
Bewick V;Cheek L;Ball J
通讯作者：
Ball J
影响因子：
3.2
作者：
Gajria K;Lu M;Sikirica V;Greven P;Zhong Y;Qin P;Xie J
通讯作者：
Xie J
影响因子：
64.3
作者：
Asherson, Philip;Buitelaar, Jan;Rohde, Luis A.
通讯作者：
Rohde, Luis A.
影响因子：
1.9
作者：
Dalsgaard, Soren;Kvist, Anette Primdal;Simonsen, Marianne
通讯作者：
Simonsen, Marianne
影响因子：
6.4
作者：
Banaschewski, Tobias;Coghill, David;Taylor, Eric
通讯作者：
Taylor, Eric