Marked improvement of diabetic diarrhea with the somatostatin analogue octreotide.
Marked improvement of diabetic diarrhea with the somatostatin analogue octreotide.
复制标题
生长抑素类似物奥曲肽显着改善糖尿病腹泻。
DOI：
10.1001/archinte.1994.00420160103014
复制
发表时间：
1994
影响因子：
--
通讯作者：
R. Takeda
中科院分区：
文献类型：
--
作者：
H. Nakabayashi;Sumie Fujii;U. Miwa;T. Seta;R. Takeda
Somatostatin and its long-acting analogue octreotide have been used in various diarrheal disorders, including neoplastic and nonneoplastic diseases of the gastrointestinal tract. In two insulin-dependent diabetic patients with autonomic neuropathy and chronic steatorrheic diarrhea refractory to conventional medications, subcutaneous administration of octreotide markedly improved the volume and frequency of stools in both patients. This change was accompanied by a clear improvement in their rapid gastrointestinal tract transit times. The treatment also greatly improved their orthostatic hypotension. No adverse effects of octreotide were observed after treatment for 7 months in one patient and 2 months in the other.
生长抑素类似物 SMS-201-995 对餐后低血压患者葡萄糖摄入的肾上腺素能反应的影响。
DOI：
10.1016/0002-9343(89)90442-7
发表时间：
1989
期刊：
The American journal of medicine
影响因子：
--
作者：
Hoeldtke,RD;Dworkin,GE;Gaspar,SR;Israel,BC;Boden,G
通讯作者：
Boden,G
胰腺霍乱综合征：合成生长抑素类似物对肠道水和离子运输的影响。
影响因子：
39.2
作者：
Santangelo,WC;O'Dorisio,TM;Kim,JG;Severino,G;Krejs,GJ
通讯作者：
Krejs,GJ
长效生长抑素类似物 SMS 201-995 对兔回肠电解质转运的体外影响。
影响因子：
29.4
作者：
Roberts,WG;Fedorak,RN;Chang,EB
通讯作者：
Chang,EB