Neuromagnetic correlates of adaptive plasticity across the hand-face border in human primary somatosensory cortex.

Neuromagnetic correlates of adaptive plasticity across the hand-face border in human primary somatosensory cortex.
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人类初级体感皮层手脸边界适应性可塑性的神经磁相关性

DOI:
10.1152/jn.00628.2015
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发表时间:
2016
影响因子:
2.5
通讯作者:
Farnè A
Farnè A
中科院分区:
医学3区
文献类型:
--
作者:
Muret D;Daligault S;Dinse HR;Delpuech C;Mattout J;Reilly KT;Farnè A

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众所周知,手传入神经阻滞或麻醉后,躯体感觉输入的永久或短暂减少会引起手-脸边界的可塑性变化,据推测,这可能是某些感知现象改变的原因,例如从脸到幻手的触觉。还已知的是,通过指尖处的重复体感刺激(RSS),手部体感输入的瞬时增加引起局部体感辨别性改善,伴随初级体感皮层(SI)中的皮层表征变化。我们最近证明,右手食指指尖的RSS诱导了类似的手-脸边界上的训练无关感知学习,改善了嘴唇的体感感知(Muret D,Dinse HR,Macchione S,Urquizar C,Farnè A,Reilly KT.Curr Biol 24:R736-R737,2014)。神经可塑性的变化是否伴随着这种遥远的和适应性的知觉可塑性,仍然是未知的。在这里,我们使用脑磁图来研究RSS引起的手-脸边界行为变化的电生理相关性。结果突出了显着的变化,偶极子位置后RSS的刺激手指和嘴唇。这些发现揭示了在增加而不是减少体感输入后,手-脸边界的塑料变化。
It is well established that permanent or transient reduction of somatosensory inputs, following hand deafferentation or anesthesia, induces plastic changes across the hand-face border, supposedly responsible for some altered perceptual phenomena such as tactile sensations being referred from the face to the phantom hand. It is also known that transient increase of hand somatosensory inputs, via repetitive somatosensory stimulation (RSS) at a fingertip, induces local somatosensory discriminative improvement accompanied by cortical representational changes in the primary somatosensory cortex (SI). We recently demonstrated that RSS at the tip of the right index finger induces similar training-independent perceptual learning across the hand-face border, improving somatosensory perception at the lips (Muret D, Dinse HR, Macchione S, Urquizar C, Farnè A, Reilly KT.Curr Biol24: R736–R737, 2014). Whether neural plastic changes across the hand-face border accompany such remote and adaptive perceptual plasticity remains unknown. Here we used magnetoencephalography to investigate the electrophysiological correlates underlying RSS-induced behavioral changes across the hand-face border. The results highlight significant changes in dipole location after RSS both for the stimulated finger and for the lips. These findings reveal plastic changes that cross the hand-face border after an increase, instead of a decrease, in somatosensory inputs.
DOI: 10.1093/brain/awv161
发表时间: 2015-08
期刊: Brain : a journal of neurology
影响因子: --
作者:
Makin TR;Scholz J;Henderson Slater D;Johansen-Berg H;Tracey I
通讯作者: Tracey I
DOI: --
发表时间: 2002
影响因子: 3
作者:
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通讯作者: M. Schweigert
DOI: 10.1093/cercor/bhn039
发表时间: 2008-12-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
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手部触感的改善会转移到面部
DOI: 10.1016/j.cub.2014.07.021
发表时间: 2014
期刊: Current Biology
影响因子: 9.2
作者:
Muret D;Dinse HR;Macchione S;Urquizar C;Farnè A;Reilly K
通讯作者: Reilly K
DOI: --
发表时间: 2005
期刊: Brain Topography
影响因子: 2.7
作者:
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通讯作者: L. Kaufman