Partial pulpotomy with two bioactive cements in permanent teeth of 6‐ to 18‐year‐old patients with signs and symptoms indicative of irreversible pulpitis: a noninferiority randomized controlled trial
Partial pulpotomy with two bioactive cements in permanent teeth of 6‐ to 18‐year‐old patients with signs and symptoms indicative of irreversible pulpitis: a noninferiority randomized controlled trial
复制标题
使用两种生物活性水泥对 6 至 18 岁患有不可逆牙髓炎体征和症状患者的恒牙进行部分活髓切断术：一项非劣效性随机对照试验
DOI：
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发表时间：
2019
影响因子：
5
通讯作者：
P. Chompu
中科院分区：
文献类型：
--
作者：
N. Uesrichai;Areerat Nirunsittirat;P. Chuveera;T. Srisuwan;T. Sastraruji;P. Chompu
目的
比较ProRoot MTA（Dentsply，塔尔萨牙科专业公司，塔尔萨，俄克拉荷马州，美国）和Biodentine（Septodont，Saint-Maur-des-Fossés，法国）两种骨水泥在6- 18岁具有不可逆性牙髓炎体征和症状的患者恒牙中进行部分活髓切断术的结局。此外，比较了由骨水泥引起的可感知的灰色变色的频率。
方法
69永久性第一磨牙的体征和症状表明不可逆的牙髓炎，从69名患者，包括在内。所有的操作者在标准化的方案下进行部分活髓切断术。使用网站生成的简单随机化编号，将牙齿分配至ProRoot MTA（37颗牙齿）或Biodentine（32颗牙齿）的部分活髓切断术，并使用复合树脂或不锈钢冠进行修复。患者每6个月被召回。要被归类为成功，被评估的牙齿必须具有临床和影像学的成功。此外，还对治疗牙齿的照片进行了评价，以确定可感知的灰色变色频率。使用Fisher精确检验比较两种骨水泥的成功率。使用卡方检验比较可感知的灰色变色的频率。百分比差异以95%置信区间估计，显著性差异水平为P < 0.05。
结果
平均随访32.2 ± 17.9个月时，共有67颗牙齿可供评估，其中37颗使用ProRoot MTA，30颗使用Biodentine。参与者的平均年龄为10 ± 2.1岁，两组之间的基线变量（性别、年龄、牙齿类型、根尖周状态、牙根发育阶段、最终修复和随访期）没有差异。两组的总体成功率均为90%，ProRoot MTA为92%，Biodentine为87%（差异为5%; 95%置信区间为-9%至19%，P = 0.487），表明Biodentine不劣于ProRoot MTA。在两组中均观察到可感知的灰色变色，ProRoot MTA治疗的牙齿为80%，Biodentine治疗的牙齿为27%，两种材料之间存在显著差异（P < 0.001）。
结论
恒牙的体征和症状表明不可逆的牙髓炎在6至18岁的患者成功地治疗了部分活髓切断术使用两种水泥。Biodentine的变色频率明显低于ProRoot MTA。
AIM
To compare the outcome of partial pulpotomy using two cements, ProRoot MTA (Dentsply, Tulsa Dental Specialties, Tulsa, OK, USA) and Biodentine (Septodont, Saint-Maur-des-Fossés, France), in permanent teeth of 6- to 18-year-old patients with signs and symptoms indicative of irreversible pulpitis. Furthermore, the frequencies of perceptible grey discoloration caused by the cements were compared.
METHODOLOGY
Sixty-nine permanent first molars with signs and symptoms indicative of irreversible pulpitis, from 69 patients, were included. All operators performed partial pulpotomy under a standardized protocol. Teeth were allocated, using a website-generated number of simple randomization, to partial pulpotomy with either ProRoot MTA (37 teeth) or Biodentine (32 teeth) and were restored with composite resin or stainless steel crowns. Patients were recalled every 6 months. To be categorized as having success, the evaluated tooth must have had both clinical and radiographic success. In addition, photographs of treated teeth were evaluated for frequency of perceptible grey discoloration. Success rates between the two cements were compared using the Fisher exact test. The frequencies of perceptible grey discoloration were compared using the chi-square test. The percentage difference was estimated by 95% confidence interval, and the level of significant difference was P < 0.05.
RESULTS
At a mean follow-up of 32.2 ± 17.9 months, a total of 67 teeth, 37 with ProRoot MTA and 30 with Biodentine, were available for evaluation. The mean age of participants was 10 ± 2.1 years and, there were no differences in the baseline variables (gender, age, tooth type, periapical status, stage of root development, final restoration and follow-up period) between the groups. The overall success in both groups was 90%, with 92% for ProRoot MTA and 87% for Biodentine (difference, 5%; 95% confidence interval, -9% to 19%, P = 0.487), suggesting that Biodentine was noninferior to ProRoot MTA. Perceptible grey discoloration was observed in both groups, 80% for teeth treated with ProRoot MTA and 27% for teeth treated with Biodentine, with a significant difference between the materials (P < 0.001).
CONCLUSIONS
Permanent teeth with signs and symptoms indicative of irreversible pulpitis in 6- to 18-year-old patients were successfully treated with partial pulpotomy using both cements. Biodentine exhibited significantly less frequency of discoloration than did ProRoot MTA.
影响因子：
4.2
作者：
KHAYAT, BG;BYERS, MR;KIMBERLY, CL
通讯作者：
KIMBERLY, CL