iNetModels 2.0: an interactive visualization and database of multi-omics data.
iNetModels 2.0: an interactive visualization and database of multi-omics data.
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DOI:
10.1093/nar/gkab254
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发表时间:
2021-07-02
影响因子:
14.9
通讯作者:
Mardinoglu A
中科院分区:
文献类型:
--
作者:
Arif M;Zhang C;Li X;Güngör C;Çakmak B;Arslantürk M;Tebani A;Özcan B;Subaş O;Zhou W;Piening B;Turkez H;Fagerberg L;Price N;Hood L;Snyder M;Nielsen J;Uhlen M;Mardinoglu A
It is essential to reveal the associations between various omics data for a comprehensive understanding of the altered biological process in human wellness and disease. To date, very few studies have focused on collecting and exhibiting multi-omics associations in a single database. Here, we present iNetModels, an interactive database and visualization platform of Multi-Omics Biological Networks (MOBNs). This platform describes the associations between the clinical chemistry, anthropometric parameters, plasma proteomics, plasma metabolomics, as well as metagenomics for oral and gut microbiome obtained from the same individuals. Moreover, iNetModels includes tissue- and cancer-specific Gene Co-expression Networks (GCNs) for exploring the connections between the specific genes. This platform allows the user to interactively explore a single feature's association with other omics data and customize its particular context (e.g. male/female specific). The users can also register their data for sharing and visualization of the MOBNs and GCNs. Moreover, iNetModels allows users who do not have a bioinformatics background to facilitate human wellness and disease research. iNetModels can be accessed freely at https://inetmodels.com without any limitation. iNetModels 2.0: an interactive visualization and database of multi-omics data.
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影响因子:
9.9
作者:
Mardinoglu A;Bjornson E;Zhang C;Klevstig M;Söderlund S;Ståhlman M;Adiels M;Hakkarainen A;Lundbom N;Kilicarslan M;Hallström BM;Lundbom J;Vergès B;Barrett PH;Watts GF;Serlie MJ;Nielsen J;Uhlén M;Smith U;Marschall HU;Taskinen MR;Boren J
通讯作者:
Boren J
DOI:
10.1038/nrg.2018.4
发表时间:
2018-05
期刊:
Nature reviews. Genetics
影响因子:
--
作者:
Karczewski KJ;Snyder MP
通讯作者:
Snyder MP
影响因子:
29
作者:
Mardinoglu A;Wu H;Bjornson E;Zhang C;Hakkarainen A;Räsänen SM;Lee S;Mancina RM;Bergentall M;Pietiläinen KH;Söderlund S;Matikainen N;Ståhlman M;Bergh PO;Adiels M;Piening BD;Granér M;Lundbom N;Williams KJ;Romeo S;Nielsen J;Snyder M;Uhlén M;Bergström G;Perkins R;Marschall HU;Bäckhed F;Taskinen MR;Borén J
通讯作者:
Borén J
影响因子:
12.3
作者:
Hasin Y;Seldin M;Lusis A
通讯作者:
Lusis A
影响因子:
16.6
作者:
Tebani, Abdellah;Gummesson, Anders;Fagerberg, Linn
通讯作者:
Fagerberg, Linn