Food for thought: association between dietary tyrosine and cognitive performance in younger and older adults.
Food for thought: association between dietary tyrosine and cognitive performance in younger and older adults.
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DOI：
10.1007/s00426-017-0957-4
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发表时间：
2019-09
期刊：
影响因子：
--
通讯作者：
Widaman KF
中科院分区：
文献类型：
--
作者：
Kühn S;Düzel S;Colzato L;Norman K;Gallinat J;Brandmaier AM;Lindenberger U;Widaman KF
事实上，酪氨酸增加多巴胺的可用性，反过来，可能会提高认知能力，导致许多研究健康的年轻参与者服用酪氨酸作为食品补充剂。作为这种饮食干预的结果，参与者在工作记忆和执行功能方面表现出性能增加。然而，迄今为止尚未研究习惯性饮食酪氨酸摄入量与认知表现之间的潜在关联。本研究的目的是澄清情节记忆（EM），工作记忆（WM）和液体智力（Gf），并在年轻和老年人酪氨酸摄入量的关联。为此，我们从柏林老龄化研究II的1724名参与者（1383名老年人，341名年轻人）中获得了习惯性酪氨酸摄入量（食物频率问卷），并使用结构方程模型对其与认知任务中广泛的认知表现进行了评估。我们观察到一个显着的关联酪氨酸摄入量和潜在的因素捕获WM，GF，和EM在年轻和老年人的样本。由于年龄组之间的部分强析因不变性对认知性能的验证性因素分析，我们能够比较酪氨酸和认知之间的关系，年龄组之间没有发现差异。除了先前关于酪氨酸食物补充剂的研究之外，本研究结果将其扩展到日常营养中习惯性酪氨酸摄入水平与认知表现（WM，GF和EM）之间的横截面关联。这证实了迄今为止从单次给药研究中得出的营养建议。
The fact that tyrosine increases dopamine availability that, in turn, may enhance cognitive performance has led to numerous studies on healthy young participants taking tyrosine as a food supplement. As a result of this dietary intervention, participants show performance increases in working memory and executive functions. However, the potential association between habitual dietary tyrosine intake and cognitive performance has not been investigated to date. The present study aims at clarifying the association of episodic memory (EM), working memory (WM) and fluid intelligence (Gf), and tyrosine intake in younger and older adults. To this end, we acquired habitual tyrosine intake (food frequency questionnaire) from 1724 participants of the Berlin Aging Study II (1383 older adults, 341 younger adults) and modelled its relations to cognitive performance assessed in a broad battery of cognitive tasks using structural equation modeling. We observed a significant association between tyrosine intake and the latent factor capturing WM, Gf, and EM in the younger and the older sample. Due to partial strong factorial invariance between age groups for a confirmatory factor analysis on cognitive performance, we were able to compare the relationship between tyrosine and cognition between age groups and found no difference. Above and beyond previous studies on tyrosine food supplementation the present result extend this to a cross-sectional association between habitual tyrosine intake levels in daily nutrition and cognitive performance (WM, Gf, and EM). This corroborates nutritional recommendations that are thus far derived from single-dose administration studies.
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DOI：
10.1080/10705519909540118
发表时间：
1999-01-01
影响因子：
6
作者：
Hu, Li-tze;Bentler, Peter M.
通讯作者：
Bentler, Peter M.
影响因子：
5.7
作者：
Karlsson, Sari;Nyberg, Lars;Backman, Lars
通讯作者：
Backman, Lars
影响因子：
7.7
作者：
Boeing, H;BohlscheidThomas, S;Wahrendorf, J
通讯作者：
Wahrendorf, J
影响因子：
7
作者：
MacCallum, RC;Browne, MW;Cai, L
通讯作者：
Cai, L
影响因子：
4.2
作者：
Kaasinen, V;Vilkman, H;Rinne, JO
通讯作者：
Rinne, JO